HitPredict

Interactor 1: FGF14 (Q92915)
Fibroblast growth factor 14 (FGF-14) (Fibroblast growth factor homologous factor 4) (FHF-4)
Gene: FGF14

Interactor 2: SCN8A (Q9UQD0)
Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6)
Gene: SCN8A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	25659151, 29359916, 22364545
Identification Methods	pull down, affinity chromatography technology, split firefly luciferase complementation, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007399 - nervous system development
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 247 Hs			1 1980
+	Hs
		1272762 FGF13_HUMAN (1-247): 1.91e-110: 319: 67.61		SCN2A_HUMAN (1-1979): 0: 1940: 73.33
+	Hs
		723843 FGF12_HUMAN (1-246): 3.07e-107: 311: 70.97		SCN1A_HUMAN (1-1968): 0: 1865: 72.73
+	Hs
		1055038 FGF14_HUMAN (1-247): 2.47e-119: 342: 100.00		SCN5A_HUMAN (3-1953): 0: 1782: 61.04
+	Hs
		1055036 FGF13_HUMAN (1-247): 1.91e-110: 319: 67.61		SCN5A_HUMAN (3-1953): 0: 1782: 61.04
+	Hs
		899630 FGF12_HUMAN (1-246): 3.07e-107: 311: 70.97		SCN5A_HUMAN (3-1953): 0: 1782: 61.04
+	Hs
		1055037 FGF11_HUMAN (3-225): 4.41e-100: 292: 61.61		SCN5A_HUMAN (3-1953): 0: 1782: 61.04