HitPredict

Interactor 1: SMRC1 (Q92922)
SWI/SNF complex subunit SMARCC1 (BRG1-associated factor 155) (BAF155) (SWI/SNF complex 155 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1)
Gene: SMARCC1

Interactor 2: SIN3A (Q96ST3)
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)
Gene: SIN3A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	11238380, 11784859, 12453419
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:1902459 - positive regulation of stem cell population maintenance
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1105 Hs			1 1273
+	Hs
		1251605 SMRC2_HUMAN (32-1105): 0: 956: 57.71		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Hs
		1302485 NCOR2_HUMAN (614-1100): 2.99e-44: 177: 15.22		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Mm
		1141044 NCOR1_MOUSE (619-981): 3.1e-33: 142: 11.75		SIN3A_MOUSE (1-1273): 0: 1542: 98.04
+	Hs
		261570 NCOR1_HUMAN (619-1062): 6.7e-30: 131: 11.55		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Sc
		609105 RSC8_YEAST (367-850): 1.21e-111: 360: 25.49		SIN3_YEAST (20-499): 1.06e-32: 140: 14.02