HitPredict

Interactor 1: RAB8B (Q92930)
Ras-related protein Rab-8B
Gene: RAB8B

Interactor 2: SYTL4 (Q96C24)
Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin)
Gene: SYTL4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	FYVE_2~Ras
Common GO terms	GO:0005768 - endosome GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 207 Hs			1 671
+	Hs
		894790 RAB8A_HUMAN (1-207): 2.52e-91: 267: 82.61		SYTL4_HUMAN (1-671): 0: 587: 100.00
+	Hs
		914274 RB11A_HUMAN (4-205): 8.61e-88: 259: 43.27		SYTL4_HUMAN (1-671): 0: 587: 100.00
+	Mm
		877205 RAB8A_MOUSE (1-207): 3.61e-91: 267: 83.58		SYTL4_MOUSE (1-671): 0: 564: 90.19
+	Hs
		914240 RB11A_HUMAN (4-205): 8.61e-88: 259: 43.27		SYTL5_HUMAN (2-669): 9.15e-161: 481: 38.17
+	Hs
		895496 RAB10_HUMAN (1-197): 7.97e-95: 276: 70.20		SYTL3_HUMAN (1-660): 8.26e-126: 387: 30.00
+	Hs
		1134943 RAB1B_HUMAN (1-204): 3.94e-92: 269: 51.96		SYT6_HUMAN (224-660): 2.2e-85: 279: 21.56
+	Hs
		894765 RAB8A_HUMAN (1-207): 2.52e-91: 267: 82.61		SYTL1_HUMAN (110-665): 1.09e-83: 276: 29.62
+	Hs
		1273014 RAB8B_HUMAN (1-207): 4.25e-93: 272: 100.00		RP3A_HUMAN (518-671): 1.14e-28: 123: 23.08
+	Mm
		812770 RAB8A_MOUSE (1-207): 3.61e-91: 267: 83.58		RP3A_MOUSE (518-671): 6.38e-29: 124: 22.49
+	Hs
		894828 RAB8A_HUMAN (1-207): 2.52e-91: 267: 82.61		RP3A_HUMAN (518-671): 1.14e-28: 123: 23.08
+	Mm
		895586 RAB10_MOUSE (1-197): 7.97e-95: 276: 70.20		RIMS1_MOUSE (108-637): 1.93e-18: 92.3: 13.94
+	Hs
		129082 RAB1A_HUMAN (1-204): 9.22e-93: 271: 52.94		SYT5_HUMAN (347-458): 3.13e-19: 92.2: 31.25