HitPredict

Interactor 1: ARHG2 (Q92974)
Rho guanine nucleotide exchange factor 2 (Guanine nucleotide exchange factor H1) (GEF-H1) (Microtubule-regulated Rho-GEF) (Proliferating cell nucleolar antigen p40)
Gene: ARHGEF2

Interactor 2: WDR83 (Q9BRX9)
WD repeat domain-containing protein 83 (Mitogen-activated protein kinase organizer 1) (MAPK organizer 1)
Gene: WDR83

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 986 Hs			1 315
+	Hs
		1273255 ARHG2_HUMAN (1-986): 0: 736: 100.00		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61
+	Hs
		903416 ARHG2_HUMAN (1-986): 0: 736: 100.00		WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60
+	Hs
		1016930 AKP13_HUMAN (37-964): 2.77e-144: 478: 35.95		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61
+	Hs
		1231083 ARG28_HUMAN (11-875): 8.11e-130: 432: 35.80		POC1B_HUMAN (2-181): 1.28e-52: 181: 21.43
+	Hs
		1049720 ARHG7_HUMAN (22-779): 1.98e-100: 335: 11.77		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61
+	Hs
		1272184 ARHG1_HUMAN (31-698): 5.2e-86: 298: 21.49		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61
+	Hs
		1137768 OBSCN_HUMAN (181-949): 2.83e-85: 304: 13.20		POC1B_HUMAN (2-181): 1.28e-52: 181: 21.43
+	Hs
		1191352 ARHG8_HUMAN (128-637): 9.09e-48: 182: 17.75		WDR83_HUMAN (1-315): 2.96e-102: 303: 100.00
+	Hs
		1202775 ARHG1_HUMAN (31-698): 5.2e-86: 298: 21.49		WDR5B_HUMAN (138-312): 8.72e-50: 170: 22.22
+	Hs
		1288351 ITSN2_HUMAN (222-599): 8.01e-67: 247: 22.90		SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47
+	Hs
		61736 A6H8W8_HUMAN (222-577): 1.82e-66: 246: 23.45		SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47