HitPredict

Interactor 1: IRF7 (Q92985)
Interferon regulatory factor 7 (IRF-7)
Gene: IRF7

Interactor 2: TBK1 (Q9UHD2)
Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)
Gene: TBK1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 0.60 0.625

The method score is based on:

Property Details
Experiments 17599067, 15367631
Identification Methods pull down, in-gel kinase assay, two hybrid
Interaction Type direct interaction, phosphorylation reaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002753 - cytoplasmic pattern recognition receptor signaling pathway
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0009615 - response to virus
and 9 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 503
Hs

1 729
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024