HitPredict

Interactor 1: KAT5 (Q92993)
Histone acetyltransferase KAT5 (EC 2.3.1.48) (60 kDa Tat-interactive protein) (Tip60) (Histone acetyltransferase HTATIP) (HIV-1 Tat interactive protein) (Lysine acetyltransferase 5) (Protein 2-hydroxyisobutyryltransferase KAT5) (EC 2.3.1.-) (Protein acetyltransferase KAT5) (EC 2.3.1.-) (Protein crotonyltransferase KAT5) (EC 2.3.1.-) (cPLA(2)-interacting protein)
Gene: KAT5

Interactor 2: H2B1A (Q96A08)
Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B)
Gene: H2BC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0035092 - sperm DNA condensation
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 513 Hs			1 127
+	Mm
		1145470 KAT5_MOUSE (1-513): 0: 852: 99.81		H2B2B_MOUSE (5-127): 1.83e-54: 168: 85.37
+	Hs
		707704 KAT5_HUMAN (1-513): 0: 852: 100.00		H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83
+	Hs
		918578 KAT5_HUMAN (1-513): 0: 852: 100.00		H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04
+	Hs
		1231219 KAT5_HUMAN (1-513): 0: 852: 100.00		H2B3B_HUMAN (1-127): 8.98e-51: 158: 85.83
+	Dm
		355268 TIP60_DROME (7-512): 0: 709: 57.60		H2B_DROME (37-127): 3.48e-47: 149: 94.51
+	Hs
		1087406 KAT8_HUMAN (162-504): 3.51e-168: 485: 46.67		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Hs
		918694 KAT8_HUMAN (162-504): 3.51e-168: 485: 46.67		H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04
+	Hs
		309661 KAT7_HUMAN (111-504): 1.86e-157: 463: 40.30		H2B1O_HUMAN (5-127): 3.41e-54: 167: 86.18
+	Hs
		309707 KAT7_HUMAN (111-504): 1.86e-157: 463: 40.30		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Hs
		309686 KAT7_HUMAN (111-504): 1.86e-157: 463: 40.30		H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04
+	Hs
		1129832 KAT6A_HUMAN (70-504): 1.5e-138: 442: 37.23		H2B2F_HUMAN (5-127): 1.83e-54: 168: 85.37
+	Hs
		1087309 KAT6A_HUMAN (70-504): 1.5e-138: 442: 37.23		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Hs
		617965 KAT6A_HUMAN (70-504): 1.5e-138: 442: 37.23		H2B1O_HUMAN (5-127): 3.41e-54: 167: 86.18
+	Hs
		1087295 KAT6B_HUMAN (144-504): 8.76e-137: 438: 40.65		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Hs
		617961 KAT6B_HUMAN (144-504): 8.76e-137: 438: 40.65		H2B1O_HUMAN (5-127): 3.41e-54: 167: 86.18
+	Hs
		1264460 KAT6B_HUMAN (144-504): 8.76e-137: 438: 40.65		H2B1H_HUMAN (5-127): 5.52e-54: 166: 85.37
+	Sc
		355855 SAS3_YEAST (208-504): 1.23e-123: 382: 40.66		H2B2_YEAST (4-126): 4.46e-41: 134: 69.36
+	Sc
		356037 ESA1_YEAST (21-103): 6e-11: 66.3: 38.10		H2B2_YEAST (4-126): 4.46e-41: 134: 69.36