Interactor 1: KAT5 (Q92993)
Histone acetyltransferase KAT5 (EC 2.3.1.48) (60 kDa Tat-interactive protein) (Tip60) (Histone acetyltransferase HTATIP) (HIV-1 Tat interactive protein) (Lysine acetyltransferase 5) (Protein 2-hydroxyisobutyryltransferase KAT5) (EC 2.3.1.-) (Protein acetyltransferase KAT5) (EC 2.3.1.-) (Protein crotonyltransferase KAT5) (EC 2.3.1.-) (cPLA(2)-interacting protein)
Gene: KAT5

Interactor 2: EP400 (Q96L91)
E1A-binding protein p400 (EC 3.6.4.-) (CAG repeat protein 32) (Domino homolog) (hDomino) (Trinucleotide repeat-containing gene 12 protein) (p400 kDa SWI2/SNF2-related protein)
Gene: EP400

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.757

The method score is based on:

Property Details
Experiments 29028833, 11509179, 20351180, 26186194, 27153538, 28514442, 23266955, 33961781, 20070254, 20946988, 17704809, 14966270
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000786 - nucleosome
GO:0000812 - Swr1 complex
GO:0003682 - chromatin binding
GO:0005654 - nucleoplasm
GO:0035267 - NuA4 histone acetyltransferase complex
and 5 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 513
Hs

1 3159
+ Dm
+ Hs
+ Sc
+ Mm
+ Hs
+ Sc
+ Sc

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Last updated: 15 Jul 2024