HitPredict

Interactor 1: KAT5 (Q92993)
Histone acetyltransferase KAT5 (EC 2.3.1.48) (60 kDa Tat-interactive protein) (Tip60) (Histone acetyltransferase HTATIP) (HIV-1 Tat interactive protein) (Lysine acetyltransferase 5) (Protein 2-hydroxyisobutyryltransferase KAT5) (EC 2.3.1.-) (Protein acetyltransferase KAT5) (EC 2.3.1.-) (Protein crotonyltransferase KAT5) (EC 2.3.1.-) (cPLA(2)-interacting protein)
Gene: KAT5

Interactor 2: EAF6 (Q9HAF1)
Chromatin modification-related protein MEAF6 (MYST/Esa1-associated factor 6) (Esa1-associated factor 6 homolog) (Protein EAF6 homolog) (hEAF6) (Sarcoma antigen NY-SAR-91)
Gene: MEAF6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.720

The method score is based on:

Property	Details
Experiments	28514442, 33961781, 26186194, 27153538, 14966270
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0000786 - nucleosome GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus and 6 others more... GO:0035267 - NuA4 histone acetyltransferase complex GO:0042981 - regulation of apoptotic process GO:0045893 - positive regulation of DNA-templated transcription GO:0051726 - regulation of cell cycle GO:1905168 - positive regulation of double-strand break repair via homologous recombination GO:2000779 - regulation of double-strand break repair
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1	513
Hs

1	191

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024