HitPredict

Interactor 1: KAT5 (Q92993)
Histone acetyltransferase KAT5 (EC 2.3.1.48) (60 kDa Tat-interactive protein) (Tip60) (Histone acetyltransferase HTATIP) (HIV-1 Tat interactive protein) (Lysine acetyltransferase 5) (Protein 2-hydroxyisobutyryltransferase KAT5) (EC 2.3.1.-) (Protein acetyltransferase KAT5) (EC 2.3.1.-) (Protein crotonyltransferase KAT5) (EC 2.3.1.-) (cPLA(2)-interacting protein)
Gene: KAT5

Interactor 2: DMAP1 (Q9NPF5)
DNA methyltransferase 1-associated protein 1 (DNMAP1) (DNMT1-associated protein 1)
Gene: DMAP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.735

The method score is based on:

Property	Details
Experiments	26186194, 27153538, 28514442, 33961781, 20946988, 14966270
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000786 - nucleosome GO:0000812 - Swr1 complex GO:0005634 - nucleus GO:0005654 - nucleoplasm and 9 others more... GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0035267 - NuA4 histone acetyltransferase complex GO:0042981 - regulation of apoptotic process GO:0045892 - negative regulation of DNA-templated transcription GO:0045893 - positive regulation of DNA-templated transcription GO:0051726 - regulation of cell cycle GO:1905168 - positive regulation of double-strand break repair via homologous recombination GO:2000779 - regulation of double-strand break repair
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	513
Hs

1	467

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024