HitPredict

Interactor 1: KAT5 (Q92993)
Histone acetyltransferase KAT5 (EC 2.3.1.48) (60 kDa Tat-interactive protein) (Tip60) (Histone acetyltransferase HTATIP) (HIV-1 Tat interactive protein) (Lysine acetyltransferase 5) (Protein 2-hydroxyisobutyryltransferase KAT5) (EC 2.3.1.-) (Protein acetyltransferase KAT5) (EC 2.3.1.-) (Protein crotonyltransferase KAT5) (EC 2.3.1.-) (cPLA(2)-interacting protein)
Gene: KAT5

Interactor 2: BRPF3 (Q9ULD4)
Bromodomain and PHD finger-containing protein 3
Gene: BRPF3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31753913
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EPL1~MOZ_SAS, EPL1~zf-MYST
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0006357 - regulation of transcription by RNA polymerase II GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 513 Hs			1 1205
+	Hs
		309758 KAT7_HUMAN (111-504): 1.86e-157: 463: 40.30		BRPF3_HUMAN (1-1205): 0: 999: 100.00
+	Hs
		1270980 KAT6A_HUMAN (70-504): 1.5e-138: 442: 37.23		BRPF3_HUMAN (1-1205): 0: 999: 100.00
+	Hs
		309682 KAT7_HUMAN (111-504): 1.86e-157: 463: 40.30		BRPF1_HUMAN (1-1202): 0: 813: 48.20
+	Hs
		876711 KAT6A_HUMAN (70-504): 1.5e-138: 442: 37.23		BRPF1_HUMAN (1-1202): 0: 813: 48.20
+	Hs
		876707 KAT6B_HUMAN (144-504): 8.76e-137: 438: 40.65		BRPF1_HUMAN (1-1202): 0: 813: 48.20
+	Hs
		1152687 KAT5_HUMAN (1-513): 0: 852: 100.00		JADE1_HUMAN (6-632): 1.24e-105: 354: 24.73
+	Hs
		319294 KAT5_HUMAN (1-513): 0: 852: 100.00		BRD1_HUMAN (680-1202): 1.71e-77: 279: 28.32
+	Hs
		309709 KAT7_HUMAN (111-504): 1.86e-157: 463: 40.30		JADE1_HUMAN (6-632): 1.24e-105: 354: 24.73
+	Hs
		1152686 KAT6A_HUMAN (70-504): 1.5e-138: 442: 37.23		JADE1_HUMAN (6-632): 1.24e-105: 354: 24.73
+	Hs
		309723 KAT7_HUMAN (111-504): 1.86e-157: 463: 40.30		JADE3_HUMAN (1-617): 3.63e-92: 317: 25.83
+	Hs
		309750 KAT7_HUMAN (111-504): 1.86e-157: 463: 40.30		JADE2_HUMAN (10-602): 3.25e-91: 313: 23.58
+	Hs
		1268046 KAT6A_HUMAN (70-504): 1.5e-138: 442: 37.23		JADE3_HUMAN (1-617): 3.63e-92: 317: 25.83
+	Hs
		1270944 KAT6A_HUMAN (70-504): 1.5e-138: 442: 37.23		JADE2_HUMAN (10-602): 3.25e-91: 313: 23.58
+	Hs
		309639 KAT7_HUMAN (111-504): 1.86e-157: 463: 40.30		BRD1_HUMAN (680-1202): 1.71e-77: 279: 28.32
+	Hs
		319291 KAT6A_HUMAN (70-504): 1.5e-138: 442: 37.23		BRD1_HUMAN (680-1202): 1.71e-77: 279: 28.32
+	Hs
		319284 KAT6B_HUMAN (144-504): 8.76e-137: 438: 40.65		BRD1_HUMAN (680-1202): 1.71e-77: 279: 28.32
+	Hs
		299074 KAT6A_HUMAN (70-504): 1.5e-138: 442: 37.23		PHF14_HUMAN (169-557): 2.2e-64: 239: 22.52
+	Hs
		309749 KAT7_HUMAN (111-504): 1.86e-157: 463: 40.30		BRD7_HUMAN (530-726): 6.55e-47: 181: 28.43
+	Hs
		309662 KAT7_HUMAN (111-504): 1.86e-157: 463: 40.30		BRD2_HUMAN (546-873): 7.08e-29: 126: 14.63
+	Hs
		309702 KAT7_HUMAN (111-504): 1.86e-157: 463: 40.30		BRD3_HUMAN (568-882): 4.36e-28: 124: 12.30