Interactor 1: UBP13 (Q92995)
Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.4.19.12) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13)
Gene: USP13

Interactor 2: CYLD (Q9NQC7)
Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD)
Gene: CYLD

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.44 0.90 0.631

The method score is based on:

Property Details
Experiments 19615732
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains UCH~UCH, UCH~zf-UBP_var
Common GO terms GO:0004843 - cysteine-type deubiquitinase activity
GO:0005829 - cytosol
GO:0006508 - proteolysis
GO:0008270 - zinc ion binding
GO:1990380 - K48-linked deubiquitinase activity
Homologous interactions 0

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Last updated: 15 Jul 2024