HitPredict

Interactor 1: DVL3 (Q92997)
Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3)
Gene: DVL3

Interactor 2: SNX27 (Q96L92)
Sorting nexin-27
Gene: SNX27

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34315543
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~PDZ
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 716 Hs			1 541
+	Mm
		1112558 DLG4_MOUSE (91-649): 6.72e-43: 167: 13.22		SNX27_MOUSE (1-541): 0: 621: 98.52
+	Mm
		1142087 DVL3_MOUSE (1-716): 4.23e-172: 512: 99.02		PZRN3_MOUSE (21-281): 2.88e-32: 134: 16.73
+	Mm
		1115920 DVL3_MOUSE (1-716): 4.23e-172: 512: 99.02		SHAN3_MOUSE (44-148): 2.57e-21: 100: 36.19
+	Mm
		844417 DVL1_MOUSE (1-716): 3.66e-157: 473: 62.83		SHAN3_MOUSE (44-148): 2.57e-21: 100: 36.19
+	Dm
		677684 DSH_DROME (3-558): 5.64e-101: 324: 46.13		DLG1_DROME (44-160): 1.73e-12: 72.3: 19.49
+	Mm
		1163969 DLG1_MOUSE (87-686): 4e-44: 172: 14.79		NEB2_MOUSE (40-314): 1.09e-33: 138: 17.98
+	Mm
		1143348 DLG4_MOUSE (91-649): 6.72e-43: 167: 13.22		NEB2_MOUSE (40-314): 1.09e-33: 138: 17.98
+	Mm
		88371 DLG4_MOUSE (91-649): 6.72e-43: 167: 13.22		SHAN1_MOUSE (43-183): 5.48e-32: 133: 30.28
+	Mm
		1143381 DLG4_MOUSE (91-649): 6.72e-43: 167: 13.22		SHAN2_MOUSE (43-147): 1.26e-28: 123: 39.05
+	Hs
		158277 DLG1_HUMAN (113-656): 1.76e-42: 167: 14.34		LIN7A_HUMAN (35-137): 4.69e-29: 116: 33.65
+	Mm
		292491 DLG1_MOUSE (87-686): 4e-44: 172: 14.79		LIN7C_MOUSE (35-136): 1.5e-27: 111: 34.95
+	Hs
		158271 DLG4_HUMAN (91-649): 2.13e-42: 166: 13.19		LIN7A_HUMAN (35-137): 4.69e-29: 116: 33.65
+	Hs
		1021563 DLG1_HUMAN (113-656): 1.76e-42: 167: 14.34		LIN7B_HUMAN (34-136): 8.8e-28: 112: 34.62
+	Hs
		1021573 DLG1_HUMAN (113-656): 1.76e-42: 167: 14.34		LIN7C_HUMAN (35-136): 1.5e-27: 111: 34.95
+	Hs
		942382 DLG4_HUMAN (91-649): 2.13e-42: 166: 13.19		LIN7B_HUMAN (34-136): 8.8e-28: 112: 34.62
+	Hs
		942387 DLG4_HUMAN (91-649): 2.13e-42: 166: 13.19		LIN7C_HUMAN (35-136): 1.5e-27: 111: 34.95
+	Mm
		1115995 DLG1_MOUSE (87-686): 4e-44: 172: 14.79		SHAN3_MOUSE (44-148): 2.57e-21: 100: 36.19
+	Mm
		936801 DLG4_MOUSE (91-649): 6.72e-43: 167: 13.22		NHRF1_MOUSE (5-248): 2.06e-23: 103: 18.95
+	Mm
		1115938 DLG4_MOUSE (91-649): 6.72e-43: 167: 13.22		SHAN3_MOUSE (44-148): 2.57e-21: 100: 36.19
+	Mm
		1143518 DLG4_MOUSE (91-649): 6.72e-43: 167: 13.22		MAGI3_MOUSE (19-356): 4.44e-13: 74.6: 16.48