HitPredict

Interactor 1: UBP7 (Q93009)
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)
Gene: USP7

Interactor 2: UBP7 (Q93009)
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)
Gene: USP7

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.909

The method score is based on:

Property Details
Experiments 27452404, 30367141, 17651432, 36243803, 16111684
Identification Methods unspecified method, affinity chromatography technology, biochemical, pull down, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains MATH~MATH, UCH~UCH, UCH~USP7_C2, USP7_C2~USP7_C2, USP7_C2~USP7_ICP0_bdg, USP7_ICP0_bdg~USP7_ICP0_bdg
Common GO terms GO:0002039 - p53 binding
GO:0004197 - cysteine-type endopeptidase activity
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 27 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024