HitPredict

Interactor 1: UBP7 (Q93009)
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)
Gene: USP7

Interactor 2: RUFY1 (Q96T51)
RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (La-binding protein 1) (Rab4-interacting protein) (Zinc finger FYVE domain-containing protein 12)
Gene: RUFY1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36282215
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1102 Hs			1 708
+	Hs
		1273954 UBP7_HUMAN (1-1102): 0: 1165: 100.00		MYH13_HUMAN (58-641): 3.14e-21: 101: 12.18
+	Hs
		1012568 UBP7_HUMAN (1-1102): 0: 1165: 100.00		CGNL1_HUMAN (210-660): 4.51e-19: 94.5: 11.84
+	Hs
		1137891 UBP7_HUMAN (1-1102): 0: 1165: 100.00		MRCKA_HUMAN (386-662): 9.1e-15: 80.6: 13.27
+	Hs
		724949 UBP7_HUMAN (1-1102): 0: 1165: 100.00		MYH9_HUMAN (362-667): 1.39e-14: 80.1: 15.66
+	Hs
		1067455 UBP7_HUMAN (1-1102): 0: 1165: 100.00		EEA1_HUMAN (326-667): 1.35e-11: 70.4: 11.92
+	Hs
		551797 UBP7_HUMAN (1-1102): 0: 1165: 100.00		DESP_HUMAN (328-650): 9.91e-10: 64.5: 13.41
+	Hs
		1273712 USP9X_HUMAN (173-554): 7.42e-97: 341: 23.08		RUFY1_HUMAN (1-708): 9.63e-73: 251: 100.00
+	Hs
		1302789 UBP24_HUMAN (200-587): 2.93e-95: 337: 24.41		RUFY1_HUMAN (1-708): 9.63e-73: 251: 100.00
+	Mm
		1113597 UBP48_MOUSE (206-572): 1.33e-102: 349: 27.45		RUFY3_MOUSE (109-527): 1.71e-31: 130: 56.33
+	Mm
		1113446 UBP48_MOUSE (206-572): 1.33e-102: 349: 27.45		MYH10_MOUSE (279-688): 1.47e-19: 96.2: 13.17
+	Hs
		1067459 UBP47_HUMAN (208-737): 3.48e-107: 368: 26.62		EEA1_HUMAN (326-667): 1.35e-11: 70.4: 11.92
+	Hs
		528398 UBP24_HUMAN (200-587): 2.93e-95: 337: 24.41		MYH6_HUMAN (76-588): 6.87e-21: 100: 11.24
+	Mm
		1113468 UBP48_MOUSE (206-572): 1.33e-102: 349: 27.45		MYH14_MOUSE (48-633): 4.06e-15: 82: 12.31
+	Mm
		1113526 UBP48_MOUSE (206-572): 1.33e-102: 349: 27.45		MYH9_MOUSE (345-666): 8.23e-14: 77.8: 15.81
+	Mm
		93872 UBP48_MOUSE (206-572): 1.33e-102: 349: 27.45		E9QPE7_MOUSE (349-665): 1.76e-09: 63.5: 12.35
+	Hs
		551869 UBP22_HUMAN (45-521): 2.51e-107: 347: 16.43		DESP_HUMAN (328-650): 9.91e-10: 64.5: 13.41
+	Hs
		725051 UBP36_HUMAN (165-651): 1.45e-94: 328: 18.13		MYH9_HUMAN (362-667): 1.39e-14: 80.1: 15.66
+	Hs
		1113861 UBP36_HUMAN (165-651): 1.45e-94: 328: 18.13		GRDN_HUMAN (312-647): 7.56e-09: 61.4: 16.95