HitPredict

Interactor 1: UBP7 (Q93009)
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)
Gene: USP7

Interactor 2: TF7L2 (Q9NQB0)
Transcription factor 7-like 2 (HMG box transcription factor 4) (T-cell-specific transcription factor 4) (T-cell factor 4) (TCF-4) (hTCF-4)
Gene: TCF7L2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	30833792
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016605 - PML body GO:0045721 - negative regulation of gluconeogenesis
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1102 Hs			1 619
+	Hs
		1273811 UBP7_HUMAN (1-1102): 0: 1165: 100.00		CIC_HUMAN (43-578): 1.85e-33: 139: 15.01
+	Hs
		727904 UBP7_HUMAN (1-1102): 0: 1165: 100.00		SOX6_HUMAN (85-501): 1.65e-33: 138: 11.66
+	Hs
		818328 UBP7_HUMAN (1-1102): 0: 1165: 100.00		SOX2_HUMAN (316-613): 5.49e-27: 113: 15.69
+	Hs
		818180 UBP34_HUMAN (125-644): 3.97e-99: 348: 18.81		SOX2_HUMAN (316-613): 5.49e-27: 113: 15.69
+	Hs
		818327 USP9X_HUMAN (173-554): 7.42e-97: 341: 23.08		SOX2_HUMAN (316-613): 5.49e-27: 113: 15.69
+	Hs
		818615 UBP24_HUMAN (200-587): 2.93e-95: 337: 24.41		SOX2_HUMAN (316-613): 5.49e-27: 113: 15.69
+	Hs
		996940 UBP36_HUMAN (165-651): 1.45e-94: 328: 18.13		SSRP1_HUMAN (333-511): 2.38e-26: 116: 18.89