Interactor 1: UBP7 (Q93009)
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)
Gene: USP7

Interactor 2: UBP21 (Q9UK80)
Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.4.19.12) (Deubiquitinating enzyme 21) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21)
Gene: USP21

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 22626734
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains UCH~UCH, UCH~USP7_C2
Common GO terms GO:0004843 - cysteine-type deubiquitinase activity
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006508 - proteolysis
Homologous interactions 16

Homologous interactions

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024