HitPredict

Interactor 1: CUL5 (Q93034)
Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1)
Gene: CUL5

Interactor 2: ASB2 (Q96Q27)
Ankyrin repeat and SOCS box protein 2 (ASB-2)
Gene: ASB2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	1.00	0.945

Property	Details
Experiments	21119685, 28514442, 33961781, 16325183, 19300455, 24044920
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cullin~SOCS_box
Common GO terms	GO:0005829 - cytosol GO:0016567 - protein ubiquitination
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 780 Hs			1 635
+	Hs
		1041153 CUL1_HUMAN (11-780): 0: 748: 27.84		ASB2_HUMAN (1-635): 4.32e-159: 472: 100.00
+	Hs
		1043172 CUL4A_HUMAN (16-780): 0: 744: 24.48		ASB2_HUMAN (1-635): 4.32e-159: 472: 100.00
+	Hs
		1041441 CUL2_HUMAN (6-780): 0: 699: 26.36		ASB2_HUMAN (1-635): 4.32e-159: 472: 100.00
+	Hs
		1274043 CUL5_HUMAN (1-780): 0: 792: 100.00		TNKS2_HUMAN (21-628): 1.28e-110: 360: 16.55
+	Hs
		1021397 CUL3_HUMAN (8-780): 0: 754: 22.96		ANK3_HUMAN (2-356): 3.48e-96: 326: 21.41
+	Hs
		1021398 CUL4A_HUMAN (16-780): 0: 744: 24.48		ANK3_HUMAN (2-356): 3.48e-96: 326: 21.41
+	Hs
		556700 CUL3_HUMAN (8-780): 0: 754: 22.96		ANK1_HUMAN (162-614): 8.21e-91: 310: 21.63
+	Hs
		63602 CUL5_HUMAN (1-780): 0: 792: 100.00		ASB14_HUMAN (63-360): 5.02e-50: 185: 20.58
+	Hs
		1264009 CUL5_HUMAN (1-780): 0: 792: 100.00		ASB15_HUMAN (239-568): 8.71e-48: 178: 17.16
+	Hs
		1042054 CUL3_HUMAN (8-780): 0: 754: 22.96		ANR52_HUMAN (4-268): 3.63e-41: 162: 15.56
+	Hs
		1274095 CUL5_HUMAN (1-780): 0: 792: 100.00		ASB3_HUMAN (412-568): 1.18e-15: 81.9: 15.66
+	Hs
		166925 CUL3_HUMAN (8-780): 0: 754: 22.96		ANR28_HUMAN (448-616): 7.06e-15: 80.4: 9.27
+	Hs
		1043332 CUL4A_HUMAN (16-780): 0: 744: 24.48		ASB3_HUMAN (412-568): 1.18e-15: 81.9: 15.66