HitPredict

Interactor 1: CUL5 (Q93034)
Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1)
Gene: CUL5

Interactor 2: ASB7 (Q9H672)
Ankyrin repeat and SOCS box protein 7 (ASB-7)
Gene: ASB7

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	1.00	0.965

Property	Details
Experiments	31253590, 33961781, 21145461, 27697924, 28514442, 16325183, 24337577
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cullin~SOCS_box
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0016567 - protein ubiquitination
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 780 Hs			1 318
+	Hs
		1274023 CUL5_HUMAN (1-780): 0: 792: 100.00		ASB2_HUMAN (3-242): 5.25e-50: 177: 21.83
+	Hs
		1274043 CUL5_HUMAN (1-780): 0: 792: 100.00		TNKS2_HUMAN (1-220): 6.85e-47: 171: 25.93
+	Hs
		1041153 CUL1_HUMAN (11-780): 0: 748: 27.84		ASB2_HUMAN (3-242): 5.25e-50: 177: 21.83
+	Hs
		1043172 CUL4A_HUMAN (16-780): 0: 744: 24.48		ASB2_HUMAN (3-242): 5.25e-50: 177: 21.83
+	Hs
		556700 CUL3_HUMAN (8-780): 0: 754: 22.96		ANK1_HUMAN (1-205): 6.14e-42: 156: 23.79
+	Hs
		862036 CUL3_HUMAN (8-780): 0: 754: 22.96		DAPK1_HUMAN (1-169): 9.59e-40: 150: 26.47
+	Hs
		1264015 CUL5_HUMAN (1-780): 0: 792: 100.00		ASB13_HUMAN (1-120): 9.64e-25: 102: 28.33
+	Hs
		1274012 CUL5_HUMAN (1-780): 0: 792: 100.00		ASB9_HUMAN (42-313): 2.27e-21: 93.6: 28.16
+	Hs
		166925 CUL3_HUMAN (8-780): 0: 754: 22.96		ANR28_HUMAN (7-174): 2.49e-32: 128: 25.44
+	Hs
		1263828 CUL5_HUMAN (1-780): 0: 792: 100.00		ASB11_HUMAN (51-314): 1.32e-19: 89.4: 27.72
+	Hs
		1041441 CUL2_HUMAN (6-780): 0: 699: 26.36		ASB2_HUMAN (3-242): 5.25e-50: 177: 21.83
+	Hs
		1262947 CUL5_HUMAN (1-780): 0: 792: 100.00		ASB5_HUMAN (1-143): 4.18e-17: 82.2: 22.38
+	Hs
		1042160 CUL3_HUMAN (8-780): 0: 754: 22.96		ASB13_HUMAN (1-120): 9.64e-25: 102: 28.33
+	Hs
		883509 CUL1_HUMAN (11-780): 0: 748: 27.84		RIPK4_HUMAN (142-311): 6.01e-22: 98.4: 13.53
+	Hs
		1041199 CUL1_HUMAN (11-780): 0: 748: 27.84		Q9H4D1_HUMAN (142-311): 1.04e-21: 97.6: 13.53
+	Hs
		1021397 CUL3_HUMAN (8-780): 0: 754: 22.96		ANK3_HUMAN (221-315): 1.91e-18: 88.4: 10.31
+	Hs
		1021398 CUL4A_HUMAN (16-780): 0: 744: 24.48		ANK3_HUMAN (221-315): 1.91e-18: 88.4: 10.31
+	Hs
		276178 CUL3_HUMAN (8-780): 0: 754: 22.96		PSD10_HUMAN (104-254): 4.63e-11: 63.5: 31.25