HitPredict

Interactor 1: VPP1 (Q93050)
V-type proton ATPase 116 kDa subunit a 1 (V-ATPase 116 kDa subunit a 1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1)
Gene: ATP6V0A1

Interactor 2: CYH2 (Q99418)
Cytohesin-2 (ARF exchange factor) (ARF nucleotide-binding site opener) (Protein ARNO) (PH, SEC7 and coiled-coil domain-containing protein 2)
Gene: CYTH2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	21307348
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 837 Hs			1 400
+	Hs
		1303450 VPP4_HUMAN (1-837): 0: 1240: 61.16		CYH2_HUMAN (1-400): 2.27e-180: 509: 100.00
+	Hs
		1303455 VPP2_HUMAN (1-830): 0: 1177: 53.53		CYH2_HUMAN (1-400): 2.27e-180: 509: 100.00
+	Mm
		551461 VPP2_MOUSE (1-824): 0: 1178: 52.96		CYH2_MOUSE (1-400): 9.2e-180: 507: 99.25
+	Hs
		1035683 VPP3_HUMAN (1-829): 0: 1068: 46.86		CYH2_HUMAN (1-400): 2.27e-180: 509: 100.00