HitPredict

Interactor 1: AT2A3 (Q93084)
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (SERCA3) (SR Ca(2+)-ATPase 3) (EC 7.2.2.10) (Calcium pump 3)
Gene: ATP2A3

Interactor 2: SRPRB (Q9Y5M8)
Signal recognition particle receptor subunit beta (SR-beta) (Protein APMCF1)
Gene: SRPRB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 999 Hs			1 271
+	Hs
		164051 AT2A1_HUMAN (1-999): 0: 946: 75.88		SRPRB_HUMAN (1-271): 4.47e-69: 216: 100.00
+	Hs
		163785 AT2A1_HUMAN (1-999): 0: 946: 75.88		ARF6_HUMAN (60-239): 5.9e-70: 215: 20.00
+	Dm
		185471 ATC1_DROME (1-997): 0: 900: 67.60		O18332_DROME (54-264): 1.27e-62: 197: 15.02
+	Dm
		611054 ATC1_DROME (1-997): 0: 900: 67.60		ARF1_DROME (46-239): 1.12e-62: 196: 22.17
+	Hs
		594732 ATP4A_HUMAN (5-989): 0: 856: 28.27		RAB1A_HUMAN (54-265): 1.14e-63: 200: 14.49
+	Hs
		393144 AT1A1_HUMAN (3-999): 0: 807: 26.96		ARF6_HUMAN (60-239): 5.9e-70: 215: 20.00
+	Hs
		164001 AT2A1_HUMAN (1-999): 0: 946: 75.88		SAR1A_HUMAN (62-195): 1.47e-11: 64: 24.63
+	Hs
		619220 AT2B4_HUMAN (5-997): 0: 767: 25.00		ARF6_HUMAN (60-239): 5.9e-70: 215: 20.00
+	Dm
		185470 ATNA_DROME (3-999): 0: 777: 27.05		O18332_DROME (54-264): 1.27e-62: 197: 15.02
+	Hs
		871987 AT12A_HUMAN (3-998): 0: 756: 26.38		SRPRB_HUMAN (1-271): 4.47e-69: 216: 100.00
+	Hs
		393122 AT1A1_HUMAN (3-999): 0: 807: 26.96		ARL4C_HUMAN (67-197): 1.37e-11: 64: 25.56