HitPredict

Interactor 1: BHMT1 (Q93088)
Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5)
Gene: BHMT

Interactor 2: BHMT1 (Q93088)
Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5)
Gene: BHMT

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.882

The method score is based on:

Property Details
Experiments 25416956, 16189514, 11223523, 31515488
Identification Methods two hybrid, x-ray crystallography, two hybrid array, two hybrid pooling approach
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains S-methyl_trans~S-methyl_trans
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006479 - protein methylation
GO:0006577 - amino-acid betaine metabolic process
GO:0006579 - amino-acid betaine catabolic process
and 6 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 406
Hs

1 406
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024