HitPredict

Interactor 1: TP4A1 (Q93096)
Protein tyrosine phosphatase type IVA 1 (EC 3.1.3.48) (PTP(CAAXI)) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1)
Gene: PTP4A1

Interactor 2: CNNM2 (Q9H8M5)
Metal transporter CNNM2 (Ancient conserved domain-containing protein 2) (Cyclin-M2)
Gene: CNNM2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.67	1.00	0.820

Property	Details
Experiments	28330616, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	CBS~DSPc
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 173 Hs			1 875
+	Hs
		1021825 TP4A2_HUMAN (4-173): 2.63e-54: 171: 87.65		CNNM2_HUMAN (1-875): 0: 1254: 100.00
+	Hs
		1159772 TP4A1_HUMAN (1-173): 8.91e-61: 187: 100.00		CNNM4_HUMAN (60-867): 0: 922: 59.98
+	Hs
		1021801 TP4A2_HUMAN (4-173): 2.63e-54: 171: 87.65		CNNM4_HUMAN (60-867): 0: 922: 59.98
+	Hs
		1274604 TP4A1_HUMAN (1-173): 8.91e-61: 187: 100.00		CNNM1_HUMAN (74-866): 0: 839: 48.59
+	Hs
		1021828 TP4A2_HUMAN (4-173): 2.63e-54: 171: 87.65		CNNM1_HUMAN (74-866): 0: 839: 48.59
+	Dm
		2649 PRL1_DROME (6-173): 4.85e-49: 158: 57.74		UEX_DROME (74-871): 0: 689: 41.30
+	Hs
		1242821 TP4A1_HUMAN (1-173): 8.91e-61: 187: 100.00		CNNM3_HUMAN (276-865): 0: 572: 48.74
+	Hs
		260582 TP4A3_HUMAN (1-172): 3.23e-57: 178: 79.07		CNNM3_HUMAN (276-865): 0: 572: 48.74
+	Hs
		1021810 TP4A2_HUMAN (4-173): 2.63e-54: 171: 87.65		CNNM3_HUMAN (276-865): 0: 572: 48.74
+	Hs
		1144582 TENS2_HUMAN (4-168): 1.8e-42: 152: 12.09		CNNM3_HUMAN (276-865): 0: 572: 48.74