Interactor 1: NEDD8 (Q93725)
NEDD8 (Neddylin) (Protein NED-8) (Ubiquitin-like protein Nedd8)
Gene: ned-8

Interactor 2: UBC12 (Q9XVK5)
NEDD8-conjugating enzyme ubc-12 (EC 2.3.2.34) (NEDD8 carrier protein) (Ubiquitin-conjugating enzyme E2 12)
Gene: ubc-12

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 10993680
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains UQ_con~ubiquitin
Common GO terms GO:0005737 - cytoplasm
GO:0043518 - negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0045116 - protein neddylation
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 77
Ce

1 180
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024