HitPredict

Interactor 1: EIF3M (Q94261)
COP9/Signalosome and eIF3 complex-shared subunit 1 (COP9 signalosome complex subunit 7) (Signalosome subunit 7) (Eukaryotic translation initiation factor 3 subunit M) (eIF3m)
Gene: cif-1

Interactor 2: CSN1 (Q9GS00)
COP9 signalosome complex subunit 1 (Signalosome subunit 1)
Gene: csn-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	17403899
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PCI~PCI, PCI~RPN7
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0008180 - COP9 signalosome GO:0048477 - oogenesis GO:0060184 - cell cycle switching and 1 others more... GO:1905879 - regulation of oogenesis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 390 Ce			1 601
+	Ce
		136315 EIF3M_CAEEL (1-390): 2.87e-130: 381: 100.00		CSN2_CAEEL (110-501): 4.43e-87: 280: 11.08
+	Hs
		122044 EIF3M_HUMAN (7-385): 6.54e-133: 387: 30.53		PSD12_HUMAN (62-521): 7.94e-78: 255: 12.25
+	Hs
		1062898 PSD13_HUMAN (93-387): 5.77e-96: 293: 16.56		PSMD6_HUMAN (108-523): 1.77e-111: 340: 15.14
+	Mm
		102351 CSN7B_MOUSE (186-388): 1.05e-56: 188: 19.61		G3UXW9_MOUSE (23-550): 4.52e-150: 444: 24.16
+	Mm
		102353 CSN7A_MOUSE (186-388): 6.77e-53: 178: 17.65		G3UXW9_MOUSE (23-550): 4.52e-150: 444: 24.16
+	Hs
		121872 PSD13_HUMAN (93-387): 5.77e-96: 293: 16.56		PSD11_HUMAN (111-529): 5.76e-103: 319: 14.69
+	Hs
		1024222 CSN7B_HUMAN (186-388): 4.2e-57: 189: 20.10		CSN1_HUMAN (44-550): 1.34e-139: 416: 24.61
+	Mm
		1207344 CSN7B_MOUSE (186-388): 1.05e-56: 188: 19.61		CSN1_MOUSE (58-550): 1.11e-139: 416: 24.35
+	Hs
		1024236 CSN7A_HUMAN (186-388): 2.65e-53: 179: 17.65		CSN1_HUMAN (44-550): 1.34e-139: 416: 24.61
+	Dm
		1180993 Q7KMP8_DROME (30-387): 2.23e-72: 232: 13.59		PSMD6_DROME (107-523): 7.33e-103: 318: 13.43
+	Hs
		122105 PSD13_HUMAN (93-387): 5.77e-96: 293: 16.56		PSD12_HUMAN (62-521): 7.94e-78: 255: 12.25
+	At
		799477 CSN7_ARATH (186-388): 4.43e-54: 181: 20.49		CSN1_ARATH (58-540): 4.73e-121: 367: 23.89
+	Dm
		1180705 Q7KMP8_DROME (30-387): 2.23e-72: 232: 13.59		PSD11_DROME (120-530): 1.48e-99: 311: 13.06
+	Sc
		978512 RPN9_YEAST (92-387): 3.68e-72: 232: 13.83		RPN6_YEAST (110-529): 1.75e-89: 285: 11.32
+	Hs
		897312 CSN7B_HUMAN (186-388): 4.2e-57: 189: 20.10		CSN2_HUMAN (85-527): 8.76e-104: 322: 10.79
+	Hs
		897324 CSN7A_HUMAN (186-388): 2.65e-53: 179: 17.65		CSN2_HUMAN (85-527): 8.76e-104: 322: 10.79
+	Dm
		1277031 CSN7_DROME (187-389): 1.73e-54: 183: 23.53		CSN2_DROME (110-527): 3.12e-100: 313: 11.42
+	Sp
		1013799 RPN9_SCHPO (112-381): 3.97e-63: 208: 15.39		RPN7_SCHPO (106-535): 1.15e-89: 285: 13.27
+	Sc
		978500 RPN9_YEAST (92-387): 3.68e-72: 232: 13.83		RPN7_YEAST (113-521): 8.2e-79: 257: 15.59
+	At
		1278364 CSN7_ARATH (186-388): 4.43e-54: 181: 20.49		PSD11_ARATH (123-531): 6.81e-97: 304: 12.32