HitPredict

Interactor 1: HDAC1 (Q94517)
Histone deacetylase HDAC1 (HD) (EC 3.5.1.98)
Gene: HDAC1

Interactor 2: Q9VCC9 (Q9VCC9)
LD23779p (Tsc1)
Gene: Tsc1

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27626673
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008340 - determination of adult lifespan GO:0048477 - oogenesis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 521 Dm			1 1100
+	Hs
		149134 HDAC2_HUMAN (2-488): 0: 659: 76.59		CTRO_HUMAN (300-1100): 4.25e-43: 174: 10.19
+	Hs
		148775 HDAC1_HUMAN (3-443): 0: 637: 81.18		CTRO_HUMAN (300-1100): 4.25e-43: 174: 10.19
+	Hs
		725212 HDAC2_HUMAN (2-488): 0: 659: 76.59		MYH10_HUMAN (612-1060): 1.09e-16: 88.1: 11.66
+	Hs
		1038808 HDAC1_HUMAN (3-443): 0: 637: 81.18		MYH2_HUMAN (364-1098): 2.26e-23: 109: 8.15
+	Hs
		1038853 HDAC1_HUMAN (3-443): 0: 637: 81.18		MYH4_HUMAN (364-1058): 1.38e-20: 100: 9.06
+	Hs
		522611 HDAC1_HUMAN (3-443): 0: 637: 81.18		MYH7_HUMAN (621-1082): 7.9e-19: 95.2: 10.73
+	Hs
		724945 HDAC2_HUMAN (2-488): 0: 659: 76.59		MYH9_HUMAN (742-1048): 2.42e-11: 70.4: 15.31
+	Hs
		1038450 HDAC1_HUMAN (3-443): 0: 637: 81.18		MRCKA_HUMAN (701-1074): 9.66e-17: 88.1: 15.91
+	Hs
		522547 HDAC1_HUMAN (3-443): 0: 637: 81.18		MYH1_HUMAN (391-847): 3.94e-14: 79.8: 11.16
+	Hs
		528410 HDAC1_HUMAN (3-443): 0: 637: 81.18		MYH8_HUMAN (387-847): 6.65e-14: 79: 10.21
+	Hs
		724813 HDAC1_HUMAN (3-443): 0: 637: 81.18		MYH9_HUMAN (742-1048): 2.42e-11: 70.4: 15.31
+	Hs
		1038481 HDAC1_HUMAN (3-443): 0: 637: 81.18		CE128_HUMAN (413-870): 1.14e-10: 68.3: 10.59
+	Hs
		702871 HDAC4_HUMAN (5-405): 2.08e-133: 415: 22.86		KINH_HUMAN (471-955): 2.01e-37: 154: 13.83
+	Hs
		1061894 HDAC6_HUMAN (9-323): 1.24e-99: 327: 23.55		SLMAP_HUMAN (625-971): 4.26e-51: 196: 18.72
+	Hs
		728525 HDAC6_HUMAN (9-323): 1.24e-99: 327: 23.55		MYH11_HUMAN (391-1075): 1.77e-24: 113: 11.67
+	Hs
		551864 HDAC6_HUMAN (9-323): 1.24e-99: 327: 23.55		DESP_HUMAN (498-1098): 1.3e-23: 111: 11.15
+	Mm
		1143175 HDAC6_MOUSE (9-323): 5.22e-101: 330: 23.85		MYH10_MOUSE (562-1044): 2.83e-19: 96.5: 11.87
+	Hs
		725261 HDAC6_HUMAN (9-323): 1.24e-99: 327: 23.55		MYH10_HUMAN (612-1060): 1.09e-16: 88.1: 11.66
+	Hs
		1268107 HDAC6_HUMAN (9-323): 1.24e-99: 327: 23.55		MY18A_HUMAN (416-842): 4.03e-15: 83.1: 12.86
+	Hs
		725053 HDAC6_HUMAN (9-323): 1.24e-99: 327: 23.55		MYH9_HUMAN (742-1048): 2.42e-11: 70.4: 15.31