HitPredict

Interactor 1: HDAC1 (Q94517)
Histone deacetylase HDAC1 (HD) (EC 3.5.1.98)
Gene: HDAC1

Interactor 2: Q9VDK5 (Q9VDK5)
Bonus, isoform A
Gene: bon

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22682252
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0006325 - chromatin organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 521 Dm			1 1133
+	Dm
		68996 HDAC1_DROME (1-521): 0: 674: 100.00		A8WHL4_DROME (1-1133): 0: 631: 99.29
+	Hs
		170436 HDAC2_HUMAN (2-488): 0: 659: 76.59		TIF1A_HUMAN (65-1116): 8.62e-118: 392: 22.11
+	Hs
		170356 HDAC1_HUMAN (3-443): 0: 637: 81.18		TIF1A_HUMAN (65-1116): 8.62e-118: 392: 22.11
+	Hs
		668870 HDAC2_HUMAN (2-488): 0: 659: 76.59		PML_HUMAN (54-622): 3.28e-73: 263: 15.46
+	Hs
		668659 HDAC1_HUMAN (3-443): 0: 637: 81.18		PML_HUMAN (54-622): 3.28e-73: 263: 15.46
+	Hs
		1171067 HDAC2_HUMAN (2-488): 0: 659: 76.59		TRI67_HUMAN (125-471): 3.14e-64: 235: 16.33
+	Mm
		936397 HDAC2_MOUSE (2-488): 0: 655: 76.18		PML_MOUSE (62-622): 3.9e-65: 239: 15.98
+	Hs
		1038479 HDAC1_HUMAN (3-443): 0: 637: 81.18		TRI67_HUMAN (125-471): 3.14e-64: 235: 16.33
+	Hs
		584952 HDAC1_HUMAN (3-443): 0: 637: 81.18		RO52_HUMAN (155-554): 2.26e-61: 219: 15.03
+	Hs
		177209 HDAC3_HUMAN (6-427): 0: 572: 56.37		PML_HUMAN (54-622): 3.28e-73: 263: 15.46
+	Hs
		177331 HDAC3_HUMAN (6-427): 0: 572: 56.37		TRI67_HUMAN (125-471): 3.14e-64: 235: 16.33
+	Hs
		1029390 HDAC1_HUMAN (3-443): 0: 637: 81.18		TIF1B_HUMAN (702-1103): 1.14e-29: 129: 17.23
+	Hs
		1270347 HDAC2_HUMAN (2-488): 0: 659: 76.59		CBP_HUMAN (443-829): 4.64e-09: 63.2: 13.04
+	Hs
		177299 HDAC3_HUMAN (6-427): 0: 572: 56.37		Q15156_HUMAN (68-455): 1.73e-31: 134: 16.41
+	Hs
		177283 HDAC3_HUMAN (6-427): 0: 572: 56.37		TIF1B_HUMAN (702-1103): 1.14e-29: 129: 17.23
+	Hs
		1038592 HDAC1_HUMAN (3-443): 0: 637: 81.18		CBP_HUMAN (443-829): 4.64e-09: 63.2: 13.04
+	Hs
		880846 HDAC4_HUMAN (5-405): 2.08e-133: 415: 22.86		TRIM1_HUMAN (71-448): 4.01e-71: 254: 15.75
+	Mm
		1157702 HDAC4_MOUSE (5-405): 1.49e-134: 418: 23.83		TRI56_MOUSE (63-560): 5.51e-65: 236: 14.96
+	Hs
		177346 HDAC3_HUMAN (6-427): 0: 572: 56.37		CBP_HUMAN (443-829): 4.64e-09: 63.2: 13.04
+	Hs
		880713 HDAC4_HUMAN (5-405): 2.08e-133: 415: 22.86		TIF1B_HUMAN (702-1103): 1.14e-29: 129: 17.23