HitPredict

Interactor 1: CUL1 (Q94AH6)
Cullin-1
Gene: CUL1

Interactor 2: AFB3 (Q9LPW7)
Protein AUXIN SIGNALING F-BOX 3
Gene: AFB3

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	15992545
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0009734 - auxin-activated signaling pathway GO:0016567 - protein ubiquitination GO:0019005 - SCF ubiquitin ligase complex
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 738 At			1 577
+	At
		1123013 CUL1_ARATH (1-738): 0: 837: 100.00		TIR1_ARATH (3-576): 1.61e-100: 318: 59.41
+	At
		1277350 CUL1_ARATH (1-738): 0: 837: 100.00		GRH1_ARATH (3-577): 2.61e-99: 315: 54.78
+	At
		137942 CUL1_ARATH (1-738): 0: 837: 100.00		COI1_ARATH (6-577): 2.55e-84: 276: 32.24
+	At
		1173680 CUL1_ARATH (1-738): 0: 837: 100.00		EBF2_ARATH (1-543): 1.45e-59: 210: 16.75
+	At
		1277334 CUL1_ARATH (1-738): 0: 837: 100.00		SKP2A_ARATH (153-344): 5.6e-17: 84.7: 21.94
+	At
		221522 CUL1_ARATH (1-738): 0: 837: 100.00		SKP2B_ARATH (153-344): 5.25e-17: 84.7: 20.41
+	At
		1277345 CUL1_ARATH (1-738): 0: 837: 100.00		EBF1_ARATH (70-311): 5.85e-15: 79.8: 17.34
+	Hs
		1041088 CUL1_HUMAN (4-738): 0: 729: 30.41		FXL14_HUMAN (4-398): 1.93e-21: 98.9: 20.00
+	Hs
		1041267 CUL1_HUMAN (4-738): 0: 729: 30.41		FBXL2_HUMAN (421-569): 7.71e-13: 72.4: 17.42
+	Hs
		1041146 CUL1_HUMAN (4-738): 0: 729: 30.41		FXL20_HUMAN (421-569): 3.71e-12: 70.5: 19.36
+	Mm
		1321914 CUL1_MOUSE (4-738): 0: 729: 30.41		FXL20_MOUSE (421-569): 4.76e-12: 70.1: 20.00
+	Hs
		1041256 CUL1_HUMAN (4-738): 0: 729: 30.41		FBXL7_HUMAN (14-178): 1.42e-11: 69: 22.89
+	Dm
		1097202 CUL1_DROME (3-738): 0: 692: 27.81		Q9VF10_DROME (37-240): 9.78e-20: 95.5: 17.86
+	Hs
		1041495 CUL2_HUMAN (1-738): 0: 688: 27.05		FBXL2_HUMAN (421-569): 7.71e-13: 72.4: 17.42