HitPredict

Interactor 1: CUL1 (Q94AH6)
Cullin-1
Gene: CUL1

Interactor 2: RCE1 (Q9SDY5)
NEDD8-conjugating enzyme Ubc12 (EC 2.3.2.-) (RUB1 carrier protein 1) (RUB1-conjugating enzyme 1)
Gene: RCE1

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	12682009
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cullin_Nedd8~UQ_con
Common GO terms	GO:0009733 - response to auxin
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 738 At			1 184
+	Hs
		1042304 CUL3_HUMAN (1-738): 0: 796: 30.09		UB2E2_HUMAN (5-174): 2.6e-77: 231: 26.32
+	Hs
		849325 CUL3_HUMAN (1-738): 0: 796: 30.09		UB2D1_HUMAN (31-175): 3.99e-78: 231: 30.82
+	Hs
		919724 CUL3_HUMAN (1-738): 0: 796: 30.09		UB2D2_HUMAN (31-175): 4.81e-78: 230: 30.14
+	Hs
		1042223 CUL3_HUMAN (1-738): 0: 796: 30.09		UB2E3_HUMAN (13-174): 3.02e-75: 226: 27.61
+	Hs
		849326 CUL4A_HUMAN (13-738): 0: 788: 34.61		UB2D1_HUMAN (31-175): 3.99e-78: 231: 30.82
+	Hs
		851812 CUL3_HUMAN (1-738): 0: 796: 30.09		UB2E1_HUMAN (8-174): 1.01e-73: 221: 25.00
+	Hs
		896074 CUL3_HUMAN (1-738): 0: 796: 30.09		UBC12_HUMAN (1-184): 1.05e-73: 221: 60.87
+	Hs
		1043149 CUL4A_HUMAN (13-738): 0: 788: 34.61		UB2E3_HUMAN (13-174): 3.02e-75: 226: 27.61
+	Hs
		895791 CUL4A_HUMAN (13-738): 0: 788: 34.61		UB2D3_HUMAN (31-175): 2.35e-76: 226: 30.14
+	Hs
		896075 CUL4A_HUMAN (13-738): 0: 788: 34.61		UBC12_HUMAN (1-184): 1.05e-73: 221: 60.87
+	Hs
		895792 CUL4B_HUMAN (12-738): 0: 774: 32.93		UB2D3_HUMAN (31-175): 2.35e-76: 226: 30.14
+	Hs
		896076 CUL4B_HUMAN (12-738): 0: 774: 32.93		UBC12_HUMAN (1-184): 1.05e-73: 221: 60.87
+	Hs
		828994 CUL4B_HUMAN (12-738): 0: 774: 32.93		UBE2A_HUMAN (28-174): 1.75e-69: 209: 25.68
+	Dm
		1213851 Q8IP45_DROME (2-738): 0: 768: 30.93		UBC2M_DROME (1-184): 9.39e-71: 213: 57.07
+	Hs
		1041136 CUL1_HUMAN (4-738): 0: 729: 30.41		UB2E3_HUMAN (13-174): 3.02e-75: 226: 27.61
+	Hs
		896072 CUL1_HUMAN (4-738): 0: 729: 30.41		UBC12_HUMAN (1-184): 1.05e-73: 221: 60.87
+	At
		1228143 CUL4_ARATH (13-738): 0: 727: 32.56		COP10_ARATH (3-174): 1.33e-68: 208: 22.54
+	Dm
		639393 CUL1_DROME (3-738): 0: 692: 27.81		UBCD1_DROME (31-175): 1.81e-77: 229: 30.14
+	Dm
		1097207 CUL1_DROME (3-738): 0: 692: 27.81		UBC2M_DROME (1-184): 9.39e-71: 213: 57.07
+	Hs
		1041134 CUL1_HUMAN (4-738): 0: 729: 30.41		UBE2F_HUMAN (15-152): 2.12e-28: 105: 38.78