HitPredict

Interactor 1: TPL (Q94AI7)
Protein TOPLESS (WUS-interacting protein 1)
Gene: TPL

Interactor 2: DRIPH (Q9LS86)
Probable E3 ubiquitin protein ligase DRIPH (EC 2.3.2.27) (DREB2A-interacting protein homolog) (RING-type E3 ubiquitin transferase DRIPH)
Gene: At3g23060

Species: Arabidopsis thaliana

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.50	0.494

Property	Details
Experiments	21798944
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1131 At			1 480
+	Hs
		254051 WDR1_HUMAN (453-1082): 3.43e-44: 172: 12.21		BMI1_HUMAN (2-311): 1.31e-75: 242: 18.46
+	Hs
		749427 TBL3_HUMAN (224-708): 3.32e-63: 233: 11.88		BRCA1_HUMAN (7-368): 1.4e-43: 167: 14.92
+	Hs
		717669 RACK1_HUMAN (386-586): 8.17e-16: 81.7: 23.47		BMI1_HUMAN (2-311): 1.31e-75: 242: 18.46
+	Hs
		717626 WDR5_HUMAN (219-386): 9.99e-09: 60.5: 10.29		BMI1_HUMAN (2-311): 1.31e-75: 242: 18.46
+	Hs
		749840 TBL1R_HUMAN (871-1121): 4.99e-26: 115: 14.07		BRCA1_HUMAN (7-368): 1.4e-43: 167: 14.92
+	Hs
		1304089 TBL1R_HUMAN (871-1121): 4.99e-26: 115: 14.07		RING2_HUMAN (1-257): 3.14e-46: 165: 14.67
+	Hs
		749353 RACK1_HUMAN (386-586): 8.17e-16: 81.7: 23.47		BRCA1_HUMAN (7-368): 1.4e-43: 167: 14.92
+	Hs
		929622 RACK1_HUMAN (386-586): 8.17e-16: 81.7: 23.47		RING2_HUMAN (1-257): 3.14e-46: 165: 14.67
+	At
		95113 GBLPA_ARATH (501-699): 5.74e-17: 85.6: 19.52		F4HUV9_ARATH (171-419): 3.47e-40: 147: 16.41
+	Hs
		749312 WDR5_HUMAN (219-386): 9.99e-09: 60.5: 10.29		BRCA1_HUMAN (7-368): 1.4e-43: 167: 14.92
+	Hs
		903455 WDR5_HUMAN (219-386): 9.99e-09: 60.5: 10.29		RING2_HUMAN (1-257): 3.14e-46: 165: 14.67
+	Mm
		903677 WDR5_MOUSE (219-386): 9.99e-09: 60.5: 10.29		RING2_MOUSE (1-257): 5.98e-46: 164: 14.67
+	Hs
		903492 WDR5_HUMAN (219-386): 9.99e-09: 60.5: 10.29		PCGF6_HUMAN (2-199): 5.48e-45: 162: 21.64
+	Hs
		903159 WDR5_HUMAN (219-386): 9.99e-09: 60.5: 10.29		RING1_HUMAN (2-94): 3.98e-25: 109: 30.11