HitPredict

Interactor 1: CSN7 (Q94JU3)
COP9 signalosome complex subunit 7 (CSN complex subunit 7) (Protein FUSCA 5)
Gene: CSN7

Interactor 2: CSN5B (Q9FVU9)
COP9 signalosome complex subunit 5b (Signalosome subunit 5b) (EC 3.4.-.-) (Jun activation domain-binding homolog 2)
Gene: CSN5B

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.775

Property	Details
Experiments	11742986, 15486099
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	JAB~PCI
Common GO terms	GO:0000338 - protein deneddylation GO:0005737 - cytoplasm GO:0008180 - COP9 signalosome GO:0009585 - red, far-red light phototransduction GO:0010387 - COP9 signalosome assembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 260 At			1 358
+	At
		1227262 CSN7_ARATH (1-260): 4.96e-98: 288: 100.00		CSN5A_ARATH (1-357): 7.16e-130: 377: 85.43
+	Dm
		1359992 CSN7_DROME (2-257): 6.25e-81: 246: 32.56		CSN5_DROME (6-339): 9.83e-123: 358: 63.77
+	Hs
		1272616 CSN7B_HUMAN (1-255): 1.99e-79: 241: 32.56		CSN5_HUMAN (1-341): 4.52e-117: 344: 66.57
+	Mm
		193524 CSN7B_MOUSE (1-255): 1.53e-78: 239: 32.56		CSN5_MOUSE (1-339): 4.47e-117: 344: 66.67
+	Hs
		1272670 CSN7A_HUMAN (12-255): 1.4e-75: 232: 30.28		CSN5_HUMAN (1-341): 4.52e-117: 344: 66.57
+	Hs
		1272702 PSD13_HUMAN (16-191): 1.36e-54: 181: 17.20		CSN5_HUMAN (1-341): 4.52e-117: 344: 66.57
+	At
		1278361 CSN7_ARATH (1-260): 4.96e-98: 288: 100.00		EIF3H_ARATH (43-350): 8.68e-73: 231: 14.73
+	Ce
		954221 EIF3M_CAEEL (2-216): 1.3e-44: 156: 19.73		CSN5_CAEEL (3-356): 9.17e-110: 326: 49.20
+	Hs
		131110 PSD13_HUMAN (16-191): 1.36e-54: 181: 17.20		PSDE_HUMAN (54-340): 1.46e-87: 268: 31.76
+	Dm
		1180994 Q7KMP8_DROME (24-191): 1.43e-51: 174: 20.23		PSDE_DROME (42-340): 1.82e-89: 272: 30.32
+	Hs
		131124 Q9Y6E3_HUMAN (16-191): 1.97e-47: 163: 16.58		PSDE_HUMAN (54-340): 1.46e-87: 268: 31.76
+	Hs
		177046 EIF3M_HUMAN (2-188): 3.07e-54: 181: 22.17		EIF3H_HUMAN (51-351): 5.53e-78: 245: 16.51
+	Ce
		284027 Q22253_CAEEL (11-191): 7.45e-51: 172: 18.85		PSDE_CAEEL (50-342): 3.76e-80: 249: 29.47
+	Dm
		1177352 EIF3M_DROME (3-205): 2.2e-53: 179: 21.70		EIF3H_DROME (40-351): 9.29e-74: 233: 17.52
+	Sc
		797570 RPN9_YEAST (11-191): 1.48e-46: 161: 15.18		RPN11_YEAST (37-340): 3.88e-80: 249: 28.75
+	Hs
		124889 EIF3M_HUMAN (2-188): 3.07e-54: 181: 22.17		EIF3F_HUMAN (30-334): 2.63e-63: 207: 12.86
+	Hs
		849285 PSD13_HUMAN (16-191): 1.36e-54: 181: 17.20		PSMD7_HUMAN (55-281): 6.31e-55: 184: 15.98
+	Dm
		640774 Q7KMP8_DROME (24-191): 1.43e-51: 174: 20.23		PSMD7_DROME (55-255): 3.73e-51: 175: 17.48
+	Hs
		849293 Q9Y6E3_HUMAN (16-191): 1.97e-47: 163: 16.58		PSMD7_HUMAN (55-281): 6.31e-55: 184: 15.98
+	Sc
		978506 RPN9_YEAST (11-191): 1.48e-46: 161: 15.18		RPN8_YEAST (57-211): 6.86e-38: 140: 23.13