HitPredict

Interactor 1: PSA5 (Q95083)
Proteasome subunit alpha type-5
Gene: Prosalpha5

Interactor 2: PSMD6 (Q9V3G7)
26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit S10) (Protein Rpn7)
Gene: Rpn7

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 244 Dm			1 389
+	Hs
		656232 PSA5_HUMAN (1-243): 9.18e-104: 302: 69.96		PSMD6_HUMAN (1-389): 1.37e-143: 414: 70.18
+	Hs
		893673 PSA6_HUMAN (4-244): 1.45e-91: 271: 26.42		PSMD6_HUMAN (1-389): 1.37e-143: 414: 70.18
+	Hs
		637690 PSA2_HUMAN (3-244): 2.6e-90: 267: 34.30		PSMD6_HUMAN (1-389): 1.37e-143: 414: 70.18
+	Dm
		771305 PSA2_DROME (3-243): 2.88e-99: 290: 30.71		PSMD6_DROME (1-389): 6.71e-134: 390: 100.00
+	Hs
		637422 PSA1_HUMAN (3-243): 7.95e-89: 265: 28.98		PSMD6_HUMAN (1-389): 1.37e-143: 414: 70.18
+	Hs
		156291 PSA7_HUMAN (7-241): 1.38e-88: 263: 34.87		PSMD6_HUMAN (1-389): 1.37e-143: 414: 70.18
+	Hs
		893660 PSA6_HUMAN (4-244): 1.45e-91: 271: 26.42		CSN1_HUMAN (15-387): 2.05e-99: 305: 19.13
+	Sc
		689209 PSA5_YEAST (1-243): 1.76e-96: 284: 57.79		RPN7_YEAST (15-389): 8.21e-95: 291: 33.83
+	Hs
		893638 PSA6_HUMAN (4-244): 1.45e-91: 271: 26.42		CSN2_HUMAN (25-383): 2.05e-97: 298: 13.19
+	Dm
		1180708 PSA5_DROME (1-244): 1.15e-107: 312: 100.00		PSD11_DROME (5-388): 9.93e-80: 253: 13.63
+	Hs
		121689 PSA5_HUMAN (1-243): 9.18e-104: 302: 69.96		PSD11_HUMAN (3-388): 1.1e-82: 260: 13.53
+	Dm
		771297 PSA2_DROME (3-243): 2.88e-99: 290: 30.71		PSD11_DROME (5-388): 9.93e-80: 253: 13.63
+	Hs
		121719 PSA6_HUMAN (4-244): 1.45e-91: 271: 26.42		PSD11_HUMAN (3-388): 1.1e-82: 260: 13.53
+	Hs
		121684 PSA2_HUMAN (3-244): 2.6e-90: 267: 34.30		PSD11_HUMAN (3-388): 1.1e-82: 260: 13.53
+	Hs
		121683 PSA1_HUMAN (3-243): 7.95e-89: 265: 28.98		PSD11_HUMAN (3-388): 1.1e-82: 260: 13.53
+	Sc
		689219 PSA5_YEAST (1-243): 1.76e-96: 284: 57.79		RPN6_YEAST (29-383): 2.71e-75: 241: 10.80
+	Hs
		121635 PSA7_HUMAN (7-241): 1.38e-88: 263: 34.87		PSD11_HUMAN (3-388): 1.1e-82: 260: 13.53
+	Sp
		1013777 PSA4_SCHPO (6-243): 4.4e-41: 142: 35.00		RPN7_SCHPO (16-387): 7.39e-104: 314: 40.84
+	Sp
		1013779 PSA4_SCHPO (6-243): 4.4e-41: 142: 35.00		RPN6_SCHPO (5-389): 2.86e-75: 241: 12.66