Interactor 1: PRIO (Q95211)
Major prion protein (PrP) (PrP27-30) (PrP33-35C) (CD antigen CD230)
Gene: PRNP

Interactor 2: PRIO (Q95211)
Major prion protein (PrP) (PrP27-30) (PrP33-35C) (CD antigen CD230)
Gene: PRNP

Species: Oryctolagus cuniculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.692

The method score is based on:

Property Details
Experiments 21041683
Identification Methods cosedimentation in solution, x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Prion~Prion, Prion_octapep~Prion_octapep
Common GO terms GO:0001540 - amyloid-beta binding
GO:0001933 - negative regulation of protein phosphorylation
GO:0002020 - protease binding
GO:0005507 - copper ion binding
GO:0005539 - glycosaminoglycan binding
and 44 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 252
Oc

1 252
+ Mm
+ Hs
+ Cl
+ Bt

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024