HitPredict

Interactor 1: Q95SH2 (Q95SH2)
Charged multivesicular body protein 1, isoform A (Charged multivesicular body protein 1, isoform B) (GH26351p)
Gene: Chmp1

Interactor 2: Q9VRJ5 (Q9VRJ5)
Charged multivesicular body protein 2b (LD36173p)
Gene: CHMP2B

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Snf7~Snf7
Common GO terms	GO:0000815 - ESCRT III complex GO:0005771 - multivesicular body GO:0015031 - protein transport GO:0032509 - endosome transport via multivesicular body sorting pathway GO:0045324 - late endosome to vacuole transport
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 203 Dm			1 212
+	At
		1013147 CHM1A_ARATH (2-200): 8.98e-41: 139: 43.72		VPS2B_ARATH (4-210): 1.28e-37: 131: 31.96
+	At
		1013164 VPS2A_ARATH (3-201): 1.37e-39: 136: 23.59		VPS2B_ARATH (4-210): 1.28e-37: 131: 31.96
+	Hs
		92838 E9PSI1_HUMAN (7-184): 2.79e-41: 150: 19.47		CHM4B_HUMAN (14-207): 5e-32: 117: 16.00
+	At
		1013166 CHM1B_ARATH (2-200): 2.88e-37: 130: 43.72		VPS2B_ARATH (4-210): 1.28e-37: 131: 31.96
+	Dm
		1362010 Q9VRJ5_DROME (4-202): 4.27e-39: 135: 19.10		Q9VBI3_DROME (2-202): 3.45e-35: 126: 33.83
+	At
		1013141 VPS2B_ARATH (4-201): 1.62e-35: 126: 24.76		VPS2B_ARATH (4-210): 1.28e-37: 131: 31.96
+	Dm
		1279485 Q95SH2_DROME (1-203): 6.08e-38: 131: 100.00		Q9VBI3_DROME (2-202): 3.45e-35: 126: 33.83
+	Sc
		732840 DID4_YEAST (4-201): 1.03e-35: 126: 22.33		DID4_YEAST (1-197): 2.32e-37: 131: 26.77
+	Dm
		1249820 Q9VRJ5_DROME (4-202): 4.27e-39: 135: 19.10		CHM4_DROME (1-187): 8.35e-33: 119: 15.87
+	Ce
		1090380 Q9U2F6_CAEEL (3-187): 6.25e-38: 132: 24.87		Q18886_CAEEL (1-211): 3.36e-33: 120: 14.82
+	Dm
		1249812 Q95SH2_DROME (1-203): 6.08e-38: 131: 100.00		CHM4_DROME (1-187): 8.35e-33: 119: 15.87
+	Dm
		1371191 Q9VRJ5_DROME (4-202): 4.27e-39: 135: 19.10		Q9VN02_DROME (5-211): 2.16e-31: 115: 25.34
+	Dm
		1373131 Q9VRJ5_DROME (4-202): 4.27e-39: 135: 19.10		CHMP5_DROME (2-193): 2.23e-31: 115: 14.07
+	At
		1322583 VPS2A_ARATH (3-201): 1.37e-39: 136: 23.59		VP241_ARATH (4-204): 1.66e-30: 113: 24.88
+	Sc
		732538 DID4_YEAST (4-201): 1.03e-35: 126: 22.33		VPS24_YEAST (9-205): 8.87e-34: 122: 24.24
+	At
		1013158 VPS2B_ARATH (4-201): 1.62e-35: 126: 24.76		VP601_ARATH (2-200): 1.71e-33: 121: 11.71
+	Dm
		1279487 Q95SH2_DROME (1-203): 6.08e-38: 131: 100.00		Q9VN02_DROME (5-211): 2.16e-31: 115: 25.34
+	Dm
		1279490 Q95SH2_DROME (1-203): 6.08e-38: 131: 100.00		CHMP5_DROME (2-193): 2.23e-31: 115: 14.07
+	Sc
		732857 DID4_YEAST (4-201): 1.03e-35: 126: 22.33		DID2_YEAST (16-210): 1.66e-29: 110: 18.27