HitPredict

Interactor 1: WLS (Q95ST2)
Protein wntless (Evenness interrupted) (Sprinter)
Gene: WLS

Interactor 2: Q9VM25 (Q9VM25)
Protein Wnt
Gene: Wnt10

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22108505
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	MIG-14_Wnt-bd~wnt
Common GO terms	GO:0016055 - Wnt signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 594 Dm			1 493
+	Dm
		452324 WLS_DROME (1-594): 0: 914: 100.00		WNTG_DROME (92-492): 2.71e-134: 398: 29.93
+	Dm
		658764 WLS_DROME (1-594): 0: 914: 100.00		WNT2_DROME (76-492): 2.14e-106: 322: 30.70
+	Dm
		776060 WLS_DROME (1-594): 0: 914: 100.00		WNT4_DROME (86-492): 3.57e-85: 274: 26.65
+	Mm
		611175 WLS_MOUSE (1-585): 0: 790: 40.65		WNT5A_MOUSE (37-492): 1.11e-126: 375: 25.84
+	Hs
		782089 WLS_HUMAN (1-585): 0: 785: 40.82		WNT5A_HUMAN (37-492): 1.35e-128: 380: 26.26
+	Mm
		382254 WLS_MOUSE (1-585): 0: 790: 40.65		WNT1_MOUSE (88-492): 1.21e-120: 359: 31.11
+	Hs
		384072 WLS_HUMAN (1-585): 0: 785: 40.82		WNT1_HUMAN (88-492): 1.18e-120: 359: 31.11
+	Dm
		658776 WLS_DROME (1-594): 0: 914: 100.00		WNT5_DROME (31-267): 2.27e-53: 195: 26.89
+	Hs
		881899 WLS_HUMAN (1-585): 0: 785: 40.82		WNT7B_HUMAN (79-492): 3.08e-107: 324: 26.79
+	Hs
		1135438 WLS_HUMAN (1-585): 0: 785: 40.82		WNT5B_HUMAN (66-492): 1.06e-104: 318: 24.94
+	Hs
		451998 WLS_HUMAN (1-585): 0: 785: 40.82		WNT2_HUMAN (73-492): 6.99e-104: 316: 27.59
+	Hs
		1135437 WLS_HUMAN (1-585): 0: 785: 40.82		WNT8A_HUMAN (101-493): 1.73e-99: 305: 26.88
+	Hs
		1135420 WLS_HUMAN (1-585): 0: 785: 40.82		WNT8B_HUMAN (101-493): 2.47e-90: 281: 24.94
+	Hs
		158076 WLS_HUMAN (1-585): 0: 785: 40.82		WNT9B_HUMAN (86-492): 9.43e-90: 280: 23.19
+	Hs
		158068 WLS_HUMAN (1-585): 0: 785: 40.82		WNT9A_HUMAN (86-492): 7.51e-80: 254: 23.02
+	Dm
		1279555 WLS_DROME (1-594): 0: 914: 100.00		Q9VM26_DROME (394-492): 2.62e-24: 107: 33.33
+	Mm
		568285 WLS_MOUSE (1-585): 0: 790: 40.65		WNT3_MOUSE (310-492): 1.45e-35: 137: 27.51
+	Hs
		881860 WLS_HUMAN (1-585): 0: 785: 40.82		WNT3A_HUMAN (310-492): 2.68e-34: 133: 27.51
+	Hs
		135861 WLS_HUMAN (1-585): 0: 785: 40.82		WNT7A_HUMAN (399-492): 7.62e-31: 124: 37.23
+	Hs
		881881 WLS_HUMAN (1-585): 0: 785: 40.82		WNT4_HUMAN (395-492): 1.02e-29: 121: 38.78