HitPredict

Interactor 1: IF2B3 (O00425)
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3) (IMP-3) (IGF-II mRNA-binding protein 3) (KH domain-containing protein overexpressed in cancer) (hKOC) (VICKZ family member 3)
Gene: IGF2BP3

Interactor 2: CBX6 (O95503)
Chromobox protein homolog 6
Gene: CBX6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 21282530
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 579 Hs			1 412
+	Hs
		316186 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00
+	Hs
		128308 IF2B3_HUMAN (1-579): 2.3e-149: 444: 100.00		CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82
+	Hs
		1335783 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82
+	Hs
		316223 IF2B2_HUMAN (79-477): 8.15e-20: 95.1: 15.50		CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00
+	Hs
		315957 PABP1_HUMAN (74-346): 1.06e-11: 69.6: 8.30		CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00
+	Hs
		1335801 IF2B2_HUMAN (79-477): 8.15e-20: 95.1: 15.50		CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82