HitPredict

Interactor 1: IF2B3 (O00425)
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3) (IMP-3) (IGF-II mRNA-binding protein 3) (KH domain-containing protein overexpressed in cancer) (hKOC) (VICKZ family member 3)
Gene: IGF2BP3

Interactor 2: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	26618866, 31324722
Identification Methods	affinity chromatography technology, cross-linking study, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 579 Hs			1 1480
+	Hs
		529152 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529153 PCBP2_HUMAN (193-484): 7.41e-30: 122: 19.05		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529983 IF2B2_HUMAN (79-477): 8.15e-20: 95.1: 15.50		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529069 PABP4_HUMAN (73-346): 8e-14: 76.6: 9.03		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529509 FUBP2_HUMAN (426-567): 1e-12: 73.1: 16.90		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		516343 PABP1_HUMAN (74-346): 1.06e-11: 69.6: 8.30		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528850 PCBP3_HUMAN (134-272): 5.55e-10: 63.3: 20.86		CFTR_HUMAN (1-1480): 0: 1031: 100.00