HitPredict

Interactor 1: IF2B3 (O00425)
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3) (IMP-3) (IGF-II mRNA-binding protein 3) (KH domain-containing protein overexpressed in cancer) (hKOC) (VICKZ family member 3)
Gene: IGF2BP3

Interactor 2: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	21319273
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0010468 - regulation of gene expression
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 579 Hs			1 298
+	Hs
		127987 IF2B3_HUMAN (1-579): 2.3e-149: 444: 100.00		CDK1_HUMAN (1-289): 7.44e-144: 408: 66.90
+	Hs
		625451 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00
+	Hs
		625547 FUBP1_HUMAN (353-559): 5.1e-29: 123: 23.22		CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00
+	Hs
		625452 PCBP2_HUMAN (193-484): 7.41e-30: 122: 19.05		CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00
+	Hs
		625540 FUBP2_HUMAN (426-567): 1e-12: 73.1: 16.90		CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00
+	Hs
		516362 PABP1_HUMAN (74-346): 1.06e-11: 69.6: 8.30		CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00
+	Hs
		841207 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		CDK7_HUMAN (2-298): 9.81e-124: 359: 44.00
+	Hs
		841288 FUBP2_HUMAN (426-567): 1e-12: 73.1: 16.90		CDK7_HUMAN (2-298): 9.81e-124: 359: 44.00