Interactor 1: HRS (Q960X8)
Hepatocyte growth factor-regulated tyrosine kinase substrate
Gene: HRS

Interactor 2: Q9XTL2 (Q9XTL2)
Jak pathway signal transduction adaptor molecule (LD02639p) (Signal transducing adaptor molecule) (Signal transducting adaptor protein)
Gene: Stam

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.64 1.00 0.801

The method score is based on:

Property Details
Experiments 14605208, 15710747
Identification Methods two hybrid, two hybrid fragment pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FYVE~VHS, VHS~VHS
Common GO terms GO:0016197 - endosomal transport
GO:0016322 - neuron remodeling
GO:0035091 - phosphatidylinositol binding
GO:0043130 - ubiquitin binding
GO:0051726 - regulation of cell cycle
and 1 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 760
Dm

1 689
+ Hs
+ Hs
+ Mm
+ Hs
+ Ce
+ Ce
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Sc
+ Sc
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024