HitPredict

Interactor 1: EIF3I (Q965S8)
Eukaryotic translation initiation factor 3 subunit I (eIF3i)
Gene: eif-3.I

Interactor 2: Q9GUP2 (Q9GUP2)
HECT-type E3 ubiquitin transferase (EC 2.3.2.26)
Gene: eel-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	30858176
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 327 Ce			1 4177
+	Hs
		125431 EIF3I_HUMAN (1-326): 1.93e-79: 246: 42.86		WWP2_HUMAN (3358-4175): 0: 638: 24.89
+	Sc
		765276 EIF3I_YEAST (1-326): 5.53e-91: 277: 39.34		RSP5_YEAST (3498-4175): 0: 583: 28.24
+	Hs
		1032165 EIF3I_HUMAN (1-326): 1.93e-79: 246: 42.86		HECW2_HUMAN (2929-4176): 6.68e-172: 579: 17.32
+	Hs
		125310 WDR5_HUMAN (126-325): 5.93e-52: 175: 16.42		WWP2_HUMAN (3358-4175): 0: 638: 24.89
+	Sc
		770524 EIF3I_YEAST (1-326): 5.53e-91: 277: 39.34		TOM1_YEAST (20-764): 5.36e-132: 470: 14.85
+	Hs
		125355 RACK1_HUMAN (5-313): 2.62e-11: 65.5: 23.82		WWP2_HUMAN (3358-4175): 0: 638: 24.89
+	Hs
		125811 STRAP_HUMAN (13-91): 1.03e-10: 63.9: 21.52		WWP2_HUMAN (3358-4175): 0: 638: 24.89
+	Hs
		929669 RACK1_HUMAN (5-313): 2.62e-11: 65.5: 23.82		SMUF1_HUMAN (3546-4174): 0: 580: 27.47
+	Hs
		1032116 EIF3I_HUMAN (1-326): 1.93e-79: 246: 42.86		HUWE1_HUMAN (2037-3559): 4.11e-79: 296: 17.05
+	Hs
		1192155 FBXW7_HUMAN (81-326): 8.26e-48: 172: 12.50		HUWE1_HUMAN (2037-3559): 4.11e-79: 296: 17.05
+	Hs
		929534 RACK1_HUMAN (5-313): 2.62e-11: 65.5: 23.82		HUWE1_HUMAN (2037-3559): 4.11e-79: 296: 17.05
+	Hs
		1192281 STRAP_HUMAN (13-91): 1.03e-10: 63.9: 21.52		HUWE1_HUMAN (2037-3559): 4.11e-79: 296: 17.05