HitPredict

Interactor 1: IF2B3 (O00425)
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3) (IMP-3) (IGF-II mRNA-binding protein 3) (KH domain-containing protein overexpressed in cancer) (hKOC) (VICKZ family member 3)
Gene: IGF2BP3

Interactor 2: YBOX1 (P67809)
Y-box-binding protein 1 (YB-1) (CCAAT-binding transcription factor I subunit A) (CBF-A) (DNA-binding protein B) (DBPB) (Enhancer factor I subunit A) (EFI-A) (Nuclease-sensitive element-binding protein 1) (Y-box transcription factor)
Gene: YBX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.839

The method score is based on:

Property Details
Experiments 35271311, 35031058, 25497084
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CSD~RRM_1
Common GO terms GO:0000932 - P-body
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 4 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 579
Hs

1 324
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Xl
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024