HitPredict

Interactor 1: SMCE1 (Q969G3)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57) (BAF57)
Gene: SMARCE1

Interactor 2: SOX17 (Q9H6I2)
Transcription factor SOX-17
Gene: SOX17

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HMG_box~HMG_box
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 411 Hs			1 414
+	Hs
		818329 SMCE1_HUMAN (1-411): 6.03e-79: 251: 100.00		SOX2_HUMAN (36-340): 1.52e-33: 129: 27.33
+	Mm
		222668 SMCE1_MOUSE (1-411): 4.03e-78: 249: 97.32		SOX2_MOUSE (61-340): 1.86e-31: 124: 26.92
+	Hs
		1199180 SMCE1_HUMAN (1-411): 6.03e-79: 251: 100.00		PB1_HUMAN (10-255): 3.17e-28: 119: 17.20
+	Hs
		727933 HM20B_HUMAN (37-302): 3.88e-47: 165: 20.51		SOX6_HUMAN (46-219): 3.19e-36: 142: 35.36
+	Hs
		1342340 HM20B_HUMAN (37-302): 3.88e-47: 165: 20.51		HM20A_HUMAN (1-167): 1.14e-35: 136: 18.61
+	Hs
		727813 HM20B_HUMAN (37-302): 3.88e-47: 165: 20.51		SOX5_HUMAN (39-195): 5.11e-34: 136: 33.33
+	Hs
		567772 UBF1_HUMAN (55-380): 1.54e-40: 155: 14.99		TF7L2_HUMAN (9-322): 6.87e-36: 140: 18.52
+	Hs
		727930 HM20A_HUMAN (3-308): 1.64e-39: 146: 16.08		SOX6_HUMAN (46-219): 3.19e-36: 142: 35.36
+	Hs
		567658 UBF1_HUMAN (55-380): 1.54e-40: 155: 14.99		SOX2_HUMAN (36-340): 1.52e-33: 129: 27.33
+	Hs
		1342331 HM20A_HUMAN (3-308): 1.64e-39: 146: 16.08		HM20A_HUMAN (1-167): 1.14e-35: 136: 18.61
+	Hs
		727808 HM20A_HUMAN (3-308): 1.64e-39: 146: 16.08		SOX5_HUMAN (39-195): 5.11e-34: 136: 33.33
+	Dm
		1212959 Q9VUD3_DROME (18-186): 1.25e-34: 136: 14.79		PANG2_DROME (14-296): 5.07e-37: 145: 15.77
+	Dm
		115539 DICH_DROME (5-165): 1.32e-36: 139: 18.52		M9PFG6_DROME (50-207): 9.32e-37: 140: 37.65
+	Hs
		818487 HM20A_HUMAN (3-308): 1.64e-39: 146: 16.08		SOX2_HUMAN (36-340): 1.52e-33: 129: 27.33
+	Hs
		881829 HM20A_HUMAN (3-308): 1.64e-39: 146: 16.08		SOX10_HUMAN (33-393): 3.12e-31: 126: 24.81
+	Dm
		1098029 DICH_DROME (5-165): 1.32e-36: 139: 18.52		DICH_DROME (14-217): 1.01e-31: 125: 31.37
+	Dm
		114457 M9PCG2_DROME (18-186): 1.17e-33: 134: 14.79		PANG1_DROME (15-296): 1.17e-25: 111: 14.48
+	Hs
		225791 HM20A_HUMAN (3-308): 1.64e-39: 146: 16.08		SOX15_HUMAN (53-144): 3.74e-20: 90.5: 55.44
+	Dm
		1098030 DICH_DROME (5-165): 1.32e-36: 139: 18.52		HMG2_DROME (63-166): 1.13e-11: 67.9: 22.64