HitPredict

Interactor 1: FBXW7 (Q969H0)
F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4)
Gene: FBXW7

Interactor 2: UHRF1 (Q96T88)
E3 ubiquitin-protein ligase UHRF1 (EC 2.3.2.27) (Inverted CCAAT box-binding protein of 90 kDa) (Nuclear protein 95) (Nuclear zinc finger protein Np95) (HuNp95) (hNp95) (RING finger protein 106) (RING-type E3 ubiquitin transferase UHRF1) (Transcription factor ICBP90) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (hUHRF1) (Ubiquitin-like-containing PHD and RING finger domains protein 1)
Gene: UHRF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 33658012
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains F-box-like~ubiquitin
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006974 - DNA damage response
GO:0016567 - protein ubiquitination
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 707
Hs

1 793
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Last updated: 15 Jul 2024