HitPredict

Interactor 1: FBXW7 (Q969H0)
F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4)
Gene: FBXW7

Interactor 2: DDX24 (Q9GZR7)
ATP-dependent RNA helicase DDX24 (EC 3.6.4.13) (DEAD box protein 24)
Gene: DDX24

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29346117
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005730 - nucleolus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 707 Hs			1 859
+	Hs
		134154 FBXW7_HUMAN (1-707): 0: 571: 100.00		DDX3X_HUMAN (158-723): 2.85e-123: 388: 19.08
+	Hs
		1281463 FBXW7_HUMAN (1-707): 0: 571: 100.00		DDX41_HUMAN (390-691): 7.07e-32: 134: 31.17
+	Hs
		1271615 FBXW7_HUMAN (1-707): 0: 571: 100.00		DDX17_HUMAN (130-267): 9.12e-12: 70.9: 21.43
+	Sc
		624089 MET30_YEAST (447-706): 5.61e-59: 212: 25.24		DBP2_YEAST (207-717): 8.32e-118: 370: 19.19
+	Hs
		1326342 NLE1_HUMAN (269-366): 5.18e-09: 61.2: 13.86		DDX24_HUMAN (1-859): 8.65e-159: 487: 100.00
+	Hs
		133956 WDR5_HUMAN (570-706): 2.64e-27: 115: 23.02		DDX3X_HUMAN (158-723): 2.85e-123: 388: 19.08
+	Hs
		571382 WDR5_HUMAN (570-706): 2.64e-27: 115: 23.02		DDX5_HUMAN (232-774): 1.14e-121: 382: 19.89
+	Hs
		181721 POC1A_HUMAN (459-659): 7.29e-18: 88.6: 27.96		DDX3Y_HUMAN (158-726): 1.41e-120: 381: 19.40
+	Hs
		134256 FBW1A_HUMAN (614-705): 2.9e-12: 72: 26.09		DDX3X_HUMAN (158-723): 2.85e-123: 388: 19.08
+	Hs
		134246 FBW1B_HUMAN (614-705): 7.05e-12: 70.5: 25.00		DDX3X_HUMAN (158-723): 2.85e-123: 388: 19.08
+	Hs
		571638 FBW1A_HUMAN (614-705): 2.9e-12: 72: 26.09		DDX5_HUMAN (232-774): 1.14e-121: 382: 19.89
+	Ca
		1124088 Q5A9A6_CANAL (496-705): 6.33e-38: 153: 23.36		DBP8_CANAL (388-712): 2.89e-39: 153: 32.43
+	Sc
		630853 NLE1_YEAST (537-705): 1.06e-34: 140: 23.50		DRS1_YEAST (391-692): 3.86e-37: 151: 35.51
+	Sc
		630886 NLE1_YEAST (537-705): 1.06e-34: 140: 23.50		HAS1_YEAST (391-743): 2.77e-35: 142: 30.25
+	Hs
		903549 WDR5_HUMAN (570-706): 2.64e-27: 115: 23.02		DDX18_HUMAN (391-740): 1.22e-32: 137: 29.69
+	Hs
		903507 WDR5_HUMAN (570-706): 2.64e-27: 115: 23.02		DDX47_HUMAN (177-261): 2.92e-12: 71.7: 36.47
+	Hs
		903410 WDR5_HUMAN (570-706): 2.64e-27: 115: 23.02		DDX17_HUMAN (130-267): 9.12e-12: 70.9: 21.43
+	Hs
		1271700 FBW1A_HUMAN (614-705): 2.9e-12: 72: 26.09		DDX17_HUMAN (130-267): 9.12e-12: 70.9: 21.43
+	Hs
		1271679 NLE1_HUMAN (269-366): 5.18e-09: 61.2: 13.86		DDX17_HUMAN (130-267): 9.12e-12: 70.9: 21.43