Interactor 1: FBXW7 (Q969H0)
F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4)
Gene: FBXW7

Interactor 2: DISC1 (Q9NRI5)
Disrupted in schizophrenia 1 protein
Gene: DISC1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 0.60 0.561

The method score is based on:

Property Details
Experiments 28727686
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0048471 - perinuclear region of cytoplasm
GO:2000060 - positive regulation of ubiquitin-dependent protein catabolic process
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 707
Hs

1 854
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024