HitPredict

Interactor 1: RNF34 (Q969K3)
E3 ubiquitin-protein ligase RNF34 (EC 2.3.2.27) (Caspase regulator CARP1) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (RING finger protein 34) (RING finger protein RIFF) (RING-type E3 ubiquitin transferase RNF34)
Gene: RNF34

Interactor 2: SPB13 (Q9UIV8)
Serpin B13 (HaCaT UV-repressible serpin) (Hurpin) (Headpin) (Peptidase inhibitor 13) (PI-13) (Proteinase inhibitor 13)
Gene: SERPINB13

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016607 - nuclear speck
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 391
+	Hs
		282541 RNF8_HUMAN (155-366): 3.49e-31: 125: 15.55		SPB3_HUMAN (1-391): 4.96e-159: 454: 57.91
+	Hs
		667956 BIRC3_HUMAN (247-372): 2e-26: 112: 24.03		SPB3_HUMAN (1-391): 4.96e-159: 454: 57.91
+	Hs
		282717 RNF8_HUMAN (155-366): 3.49e-31: 125: 15.55		SPB12_HUMAN (1-391): 1.06e-148: 428: 41.98
+	Hs
		1035986 BIRC3_HUMAN (247-372): 2e-26: 112: 24.03		SPB12_HUMAN (1-391): 1.06e-148: 428: 41.98