HitPredict

Interactor 1: IF2B3 (O00425)
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3) (IMP-3) (IGF-II mRNA-binding protein 3) (KH domain-containing protein overexpressed in cancer) (hKOC) (VICKZ family member 3)
Gene: IGF2BP3

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned1853
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 579 Hs			1 2527
+	Hs
		1130670 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1121934 Q53SS8_HUMAN (277-508): 3.85e-32: 129: 24.14		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		72991 B4DT31_HUMAN (395-559): 3.48e-29: 124: 27.22		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130419 FUBP1_HUMAN (353-559): 5.1e-29: 123: 23.22		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1072105 PCBP2_HUMAN (193-484): 7.41e-30: 122: 19.05		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		101785 F8W930_HUMAN (79-477): 6.94e-20: 95.4: 15.76		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130448 FUBP3_HUMAN (189-414): 5.52e-18: 89.3: 14.17		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130201 Q6IQ30_HUMAN (73-346): 9.55e-14: 76.2: 9.03		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130402 FUBP2_HUMAN (426-567): 1e-12: 73.1: 16.90		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		516547 PABP1_HUMAN (74-346): 1.06e-11: 69.6: 8.30		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		101720 F8VZX2_HUMAN (482-575): 2.57e-10: 64.1: 18.09		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		73054 B4DUQ1_HUMAN (119-267): 1.32e-09: 62.7: 16.78		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Zm
		36451 B7ZYR3_MAIZE (146-557): 3.11e-50: 185: 15.51		A0A1D6M0R8_MAIZE (1836-2183): 3.97e-100: 335: 24.61