HitPredict

Interactor 1: TRI63 (Q969Q1)
E3 ubiquitin-protein ligase TRIM63 (EC 2.3.2.27) (Iris RING finger protein) (Muscle-specific RING finger protein 1) (MuRF-1) (MuRF1) (RING finger protein 28) (RING-type E3 ubiquitin transferase TRIM63) (Striated muscle RING zinc finger protein) (Tripartite motif-containing protein 63)
Gene: TRIM63

Interactor 2: TBA8 (Q9NY65)
Tubulin alpha-8 chain (EC 3.6.5.-) (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Cleaved into: Dephenylalaninated tubulin alpha-8 chain]
Gene: TUBA8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	18157088, 32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005874 - microtubule
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 353 Hs			1 449
+	Hs
		1309481 TRIM6_HUMAN (10-348): 1.81e-70: 229: 16.14		TBA1C_HUMAN (1-449): 0: 717: 89.76
+	Hs
		585085 RO52_HUMAN (8-353): 2.82e-75: 241: 14.74		TBA8_HUMAN (1-449): 0: 700: 100.00
+	Hs
		1175047 TRI58_HUMAN (8-353): 5.49e-73: 235: 13.87		TBA1A_HUMAN (1-439): 0: 704: 90.89
+	Hs
		1317463 TRI54_HUMAN (7-326): 7.72e-74: 234: 61.37		TBA8_HUMAN (1-449): 0: 700: 100.00
+	Hs
		1317527 TRI55_HUMAN (11-324): 8.5e-72: 234: 61.78		TBA8_HUMAN (1-449): 0: 700: 100.00
+	Hs
		933631 TRI36_HUMAN (3-338): 7.29e-66: 222: 25.06		TBA4A_HUMAN (1-448): 0: 710: 89.96
+	Hs
		1175202 TRI36_HUMAN (3-338): 7.29e-66: 222: 25.06		TBA1A_HUMAN (1-439): 0: 704: 90.89
+	Hs
		175670 TRI18_HUMAN (43-337): 4.87e-65: 219: 23.65		TBA1B_HUMAN (1-439): 0: 706: 90.89
+	Hs
		537100 TRI27_HUMAN (8-353): 1.89e-68: 225: 17.49		TBA8_HUMAN (1-449): 0: 700: 100.00
+	Hs
		175725 TRI18_HUMAN (43-337): 4.87e-65: 219: 23.65		TBA8_HUMAN (1-449): 0: 700: 100.00
+	Hs
		1309480 TRI31_HUMAN (8-301): 3.28e-59: 198: 21.77		TBA1C_HUMAN (1-449): 0: 717: 89.76
+	Hs
		1318713 TRIM5_HUMAN (10-346): 1.16e-64: 214: 17.49		TBA8_HUMAN (1-449): 0: 700: 100.00
+	Hs
		175631 TRI18_HUMAN (43-337): 4.87e-65: 219: 23.65		TBB5_HUMAN (1-439): 0: 694: 39.41
+	Hs
		933388 TRIM1_HUMAN (14-345): 3.61e-59: 205: 22.00		TBA1B_HUMAN (1-439): 0: 706: 90.89
+	Hs
		175671 TRI18_HUMAN (43-337): 4.87e-65: 219: 23.65		TBB4B_HUMAN (1-437): 0: 691: 39.13
+	Hs
		933342 TRI31_HUMAN (8-301): 3.28e-59: 198: 21.77		TBA1B_HUMAN (1-439): 0: 706: 90.89
+	Hs
		428490 TRIM1_HUMAN (14-345): 3.61e-59: 205: 22.00		TBB5_HUMAN (1-439): 0: 694: 39.41
+	Hs
		934017 TRIM1_HUMAN (14-345): 3.61e-59: 205: 22.00		TBB4B_HUMAN (1-437): 0: 691: 39.13
+	Hs
		428414 TRI31_HUMAN (8-301): 3.28e-59: 198: 21.77		TBB5_HUMAN (1-439): 0: 694: 39.41
+	Hs
		933960 TRI31_HUMAN (8-301): 3.28e-59: 198: 21.77		TBB4B_HUMAN (1-437): 0: 691: 39.13