HitPredict

Interactor 1: LMBL2 (Q969R5)
Lethal(3)malignant brain tumor-like protein 2 (H-l(3)mbt-like protein 2) (L(3)mbt-like protein 2)
Gene: L3MBTL2

Interactor 2: PCGF1 (Q9BSM1)
Polycomb group RING finger protein 1 (Nervous system Polycomb-1) (NSPc1) (RING finger protein 68)
Gene: PCGF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 705 Hs			1 259
+	Hs
		718083 LMBL2_HUMAN (1-705): 0: 1012: 100.00		BMI1_HUMAN (30-255): 1.92e-63: 203: 35.29
+	Hs
		718416 LMBL2_HUMAN (1-705): 0: 1012: 100.00		PCGF2_HUMAN (30-255): 4.65e-59: 192: 35.57
+	Hs
		1108529 LMBL2_HUMAN (1-705): 0: 1012: 100.00		PCGF3_HUMAN (32-257): 1.89e-56: 182: 38.68
+	Hs
		1282142 LMBL2_HUMAN (1-705): 0: 1012: 100.00		PCGF6_HUMAN (26-252): 6.21e-45: 156: 36.05
+	Hs
		1197577 LMBL2_HUMAN (1-705): 0: 1012: 100.00		PCGF5_HUMAN (30-257): 3.38e-44: 151: 29.41
+	Hs
		1282132 LMBL2_HUMAN (1-705): 0: 1012: 100.00		RING2_HUMAN (24-259): 7.12e-39: 140: 16.88
+	Mm
		886508 LMBL2_MOUSE (1-705): 0: 1001: 90.92		PCGF6_MOUSE (26-252): 3.04e-42: 149: 36.48
+	Mm
		886509 LMBL2_MOUSE (1-705): 0: 1001: 90.92		RING2_MOUSE (24-259): 5.08e-39: 140: 16.88
+	Hs
		988004 LMBL2_HUMAN (1-705): 0: 1012: 100.00		RING1_HUMAN (24-155): 3.14e-32: 123: 20.59
+	Mm
		1160052 MBTD1_MOUSE (64-604): 0: 756: 61.14		RING2_MOUSE (24-259): 5.08e-39: 140: 16.88
+	Hs
		1292153 SCMH1_HUMAN (167-402): 7.35e-79: 267: 28.03		PCGF1_HUMAN (1-259): 4.13e-82: 248: 100.00
+	Hs
		718098 SCMH1_HUMAN (167-402): 7.35e-79: 267: 28.03		BMI1_HUMAN (30-255): 1.92e-63: 203: 35.29
+	Hs
		718330 SCML2_HUMAN (159-392): 8.81e-79: 267: 25.96		BMI1_HUMAN (30-255): 1.92e-63: 203: 35.29
+	Hs
		718418 SCMH1_HUMAN (167-402): 7.35e-79: 267: 28.03		PCGF2_HUMAN (30-255): 4.65e-59: 192: 35.57
+	Hs
		1108531 SCMH1_HUMAN (167-402): 7.35e-79: 267: 28.03		PCGF3_HUMAN (32-257): 1.89e-56: 182: 38.68
+	Hs
		1197578 SCMH1_HUMAN (167-402): 7.35e-79: 267: 28.03		PCGF5_HUMAN (30-257): 3.38e-44: 151: 29.41
+	Mm
		1225135 SCMH1_MOUSE (167-394): 1.83e-78: 267: 28.57		RING2_MOUSE (24-259): 5.08e-39: 140: 16.88
+	Hs
		1292152 SCMH1_HUMAN (167-402): 7.35e-79: 267: 28.03		RING2_HUMAN (24-259): 7.12e-39: 140: 16.88
+	Hs
		1304185 SCML2_HUMAN (159-392): 8.81e-79: 267: 25.96		RING2_HUMAN (24-259): 7.12e-39: 140: 16.88
+	Hs
		988007 SCMH1_HUMAN (167-402): 7.35e-79: 267: 28.03		RING1_HUMAN (24-155): 3.14e-32: 123: 20.59