Interactor 1: ZN622 (Q969S3)
Cytoplasmic 60S subunit biogenesis factor ZNF622 (Zinc finger protein 622) (Zinc finger-like protein 9)
Gene: ZNF622
Interactor 2: M3K5 (Q99683)
Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5)
Gene: MAP3K5
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.62 | 0.60 | 0.612 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 21771788 |
| Identification Methods | comigration in gel electrophoresis, anti bait coimmunoprecipitation, in-gel kinase assay, pull down |
| Interaction Type | direct interaction, physical association, association, phosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005829 - cytosol GO:0008631 - intrinsic apoptotic signaling pathway in response to oxidative stress GO:0043065 - positive regulation of apoptotic process GO:0046330 - positive regulation of JNK cascade |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
