HitPredict

Interactor 1: UB2E3 (Q969T4)
Ubiquitin-conjugating enzyme E2 E3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E3) (UbcH9) (Ubiquitin carrier protein E3) (Ubiquitin-conjugating enzyme E2-23 kDa) (Ubiquitin-protein ligase E3)
Gene: UBE2E3

Interactor 2: TRI54 (Q9BYV2)
Tripartite motif-containing protein 54 (Muscle-specific RING finger protein) (MuRF) (Muscle-specific RING finger protein 3) (MuRF-3) (MuRF3) (RING finger protein 30)
Gene: TRIM54

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.80	0.687

Property	Details
Experiments	23695783, 31391242
Identification Methods	pull down, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 207 Hs			1 358
+	Hs
		1282363 UB2E3_HUMAN (1-207): 5.71e-90: 264: 100.00		TRIM1_HUMAN (17-333): 6.09e-86: 276: 22.62
+	Hs
		1297378 UB2E2_HUMAN (1-207): 5.59e-89: 261: 85.02		TRIM1_HUMAN (17-333): 6.09e-86: 276: 22.62
+	Hs
		1282343 UB2E3_HUMAN (1-207): 5.71e-90: 264: 100.00		TRI55_HUMAN (1-328): 3.79e-76: 246: 65.24
+	Hs
		1281989 UB2E3_HUMAN (1-207): 5.71e-90: 264: 100.00		TRI63_HUMAN (8-328): 1.02e-74: 236: 60.44
+	Hs
		1282350 UB2E3_HUMAN (1-207): 5.71e-90: 264: 100.00		TRI39_HUMAN (17-358): 1.52e-70: 230: 17.87
+	Hs
		1282345 UB2E3_HUMAN (1-207): 5.71e-90: 264: 100.00		TRIM2_HUMAN (14-353): 9.22e-68: 228: 19.03
+	Hs
		1297370 UB2E2_HUMAN (1-207): 5.59e-89: 261: 85.02		TRI39_HUMAN (17-358): 1.52e-70: 230: 17.87
+	Hs
		536965 UB2E3_HUMAN (1-207): 5.71e-90: 264: 100.00		TRI27_HUMAN (11-358): 2.55e-69: 227: 17.30
+	Hs
		1297367 UB2E2_HUMAN (1-207): 5.59e-89: 261: 85.02		TRIM2_HUMAN (14-353): 9.22e-68: 228: 19.03
+	Hs
		536996 UB2E2_HUMAN (1-207): 5.59e-89: 261: 85.02		TRI27_HUMAN (11-358): 2.55e-69: 227: 17.30
+	Hs
		262192 UB2E2_HUMAN (1-207): 5.59e-89: 261: 85.02		TRIM3_HUMAN (14-353): 4.27e-64: 218: 19.71
+	Hs
		135036 UB2E3_HUMAN (1-207): 5.71e-90: 264: 100.00		TRI38_HUMAN (11-357): 9.66e-64: 211: 18.05
+	Hs
		135040 UB2E2_HUMAN (1-207): 5.59e-89: 261: 85.02		TRI38_HUMAN (11-357): 9.66e-64: 211: 18.05
+	Hs
		175703 UB2E3_HUMAN (1-207): 5.71e-90: 264: 100.00		TRI18_HUMAN (46-333): 8.71e-60: 205: 22.49
+	Hs
		175710 UB2E2_HUMAN (1-207): 5.59e-89: 261: 85.02		TRI18_HUMAN (46-333): 8.71e-60: 205: 22.49
+	Hs
		1297366 UB2E2_HUMAN (1-207): 5.59e-89: 261: 85.02		TRI31_HUMAN (11-303): 1.56e-60: 202: 22.53
+	Hs
		135045 UB2D4_HUMAN (61-206): 1.19e-82: 243: 63.01		TRI38_HUMAN (11-357): 9.66e-64: 211: 18.05
+	Hs
		175730 UB2D4_HUMAN (61-206): 1.19e-82: 243: 63.01		TRI18_HUMAN (46-333): 8.71e-60: 205: 22.49
+	Hs
		1204900 UB2E3_HUMAN (1-207): 5.71e-90: 264: 100.00		TRI50_HUMAN (16-270): 9.01e-13: 70.9: 25.10
+	Hs
		1204902 UB2E2_HUMAN (1-207): 5.59e-89: 261: 85.02		TRI50_HUMAN (16-270): 9.01e-13: 70.9: 25.10